(Q45865892)

17 December 2017

title

Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes (English)

1 reference

17 December 2017

author

James Birchall

series ordinal

1

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17 December 2017

Mark Gumbleton

series ordinal

3

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17 December 2017

author name string

I W Kellaway

series ordinal

2

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17 December 2017

language of work or name

English

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publication date

1 March 2000

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17 December 2017

International Journal of Pharmaceutics

published in

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17 December 2017

volume

197

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17 December 2017

issue

1-2

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17 December 2017

page(s)

221-231

1 reference

17 December 2017

Towards gene therapy for cystic fibrosis: a clinical progress report.

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7 January 2021

Maintenance of transfection rates and physical characterization of lipid/DNA complexes after freeze-drying and rehydration

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Physico-chemical characterisation and transfection efficiency of lipid-based gene delivery complexes

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Aerosol and intravenous transfection of human alpha 1-antitrypsin gene to lungs of rabbits

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Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene

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Gene therapy strategies for asthma

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Aerosolization of cationic lipid:pDNA complexes--in vitro optimization of nebulizer parameters for human clinical studies

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Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes

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Potentiation of cationic liposome-mediated gene delivery by polycations

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Cystic fibrosis clinical trials

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Increased expression of DNA cointroduced with nuclear protein in adult rat liver

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Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung

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In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes

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Development of targeted delivery systems for nucleic acid drugs

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Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

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7 January 2021

Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids

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7 January 2021

Design of a short membrane-destabilizing peptide covalently bound to liposomes

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7 January 2021

From genes to gene medicines: recent advances in nonviral gene delivery

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7 January 2021

Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung

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7 January 2021

Airway delivery of cationic lipid: DNA complexes for cystic fibrosis

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7 January 2021

Toward development of a non-viral gene therapeutic

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7 January 2021

Protamine sulfate enhances lipid-mediated gene transfer

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7 January 2021

The effects of jet nebulisation on cationic liposome-mediated gene transfer in vitro

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7 January 2021

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

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7 January 2021

10.1016/S0378-5173(00)00339-2

Identifiers

DOI

1 reference

17 December 2017

1 reference

17 December 2017