(Q45867266)

English

Gene gun-mediated delivery of an interleukin-12 expression plasmid protects against infections with the intracellular protozoan parasites Leishmania major and Trypanosoma cruzi in mice

scientific article published in April 2000

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

Gene gun-mediated delivery of an interleukin-12 expression plasmid protects against infections with the intracellular protozoan parasites Leishmania major and Trypanosoma cruzi in mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

Trypanosoma cruzi

0 references

Leishmania major

object named as

Leishmania major

1 reference

based on heuristic

inferred from title

5

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

author name string

T Sakai

1

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

H Hisaeda

2

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

Y Nakano

3

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

H Ishikawa

4

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

K Ishii

6

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

Y Nitta

7

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

J Miyazaki

8

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

K Himeno

9

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

publication date

1 April 2000

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

99

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

4

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

615-624

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization.

1 reference

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Modulation of virus-induced delayed-type hypersensitivity by plasmid DNA encoding the cytokine interleukin-10.

1 reference

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Cytokines induce the development of functionally heterogeneous T helper cell subsets

1 reference

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Gene vaccination: plasmid DNA is more than just a blueprint

1 reference

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26 August 2018

Interleukin-12 is indispensable for protective immunity against Leishmania major

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Cytokine gene therapy of cancer using gene gun technology: superior antitumor activity of interleukin-12.

1 reference

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Suppression of ongoing ocular inflammatory disease by topical administration of plasmid DNA encoding IL-10.

1 reference

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26 August 2018

Interleukin-12-mediated resistance to Trypanosoma cruzi is dependent on tumor necrosis factor alpha and gamma interferon.

1 reference

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26 August 2018

Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells

1 reference

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26 August 2018

In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment

1 reference

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26 August 2018

Differential susceptibilities of mice genomically deleted of CD4 and CD8 to infections with Trypanosoma cruzi or Trypanosoma brucei.

1 reference

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26 August 2018

IL-12 induces the production of IFN-gamma by neonatal human CD4 T cells.

1 reference

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26 August 2018

Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response

1 reference

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26 August 2018

Recombinant interleukin 12 cures mice infected with Leishmania major

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

IL-10 mediates susceptibility to Trypanosoma cruzi infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids

1 reference

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26 August 2018

In vivo cytokine gene transfer by gene gun reduces tumor growth in mice

1 reference

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26 August 2018

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

The role of TH1 and TH2 cells in experimental cutaneous leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Role of T helper/inducer cells as well as natural killer cells in resistance to Trypanosoma cruzi infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

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In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2327200

26 August 2018

Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice.

1 reference

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26 August 2018

Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1- and Th2-like cell lines

1 reference

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26 August 2018

Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection

1 reference

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

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Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection

1 reference

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26 August 2018

Role of the production of natural killer cell stimulatory factor (NKSF/IL-12) in the ability of B cell lines to stimulate T and NK cell proliferation

1 reference

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Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ-dependent

1 reference

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21 January 2018

Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease

3 references

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2000.00989.X

21 January 2018

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1 December 2018

https://pubmed.ncbi.nlm.nih.gov/10792510

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1 reference

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Outcome of infection with different strains of Trypanosoma cruzi in mice lacking CD4 and/or CD8

1 reference

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1 December 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/10792510

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DNA-based immunization by in vivo transfection of dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10792510

12 December 2020

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inferred from PubMed ID database lookup

Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10792510

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-12: a cytokine at the interface of inflammation and immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10792510

12 December 2020

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inferred from PubMed ID database lookup

Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10792510

12 December 2020

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1 reference

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1 reference

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Identifiers

10.1046/J.1365-2567.2000.00989.X

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/10792510

ResearchGate publication ID

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