(Q45869303)

English

Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma.

scientific article published in October 2003

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scholarly article

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Europe PubMed Central

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19 December 2019

Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14529827%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

Hidetsugu Asada

2

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19 December 2019

author name string

Tsunao Kishida

1

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19 December 2019

Yoshiki Itokawa

3

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19 December 2019

Feng-De Cui

4

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19 December 2019

Masaharu Shin-Ya

5

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19 December 2019

Satoshi Gojo

6

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19 December 2019

Kakei Yasutomi

7

1 reference

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19 December 2019

Yuji Ueda

8

1 reference

Europe PubMed Central

PubMed publication ID

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19 December 2019

Hisakazu Yamagishi

9

1 reference

Europe PubMed Central

PubMed publication ID

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19 December 2019

Jiro Imanishi

10

1 reference

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19 December 2019

Osam Mazda

11

1 reference

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19 December 2019

publication date

1 October 2003

1 reference

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19 December 2019

Molecular Therapy

1 reference

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14529827%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

8

1 reference

Europe PubMed Central

PubMed publication ID

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19 December 2019

4

1 reference

Europe PubMed Central

PubMed publication ID

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19 December 2019

552-558

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14529827%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

Cytokine therapy for cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line C(epsilon) transcription of IL-4-stimulated B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

A critical role for IL-21 in regulating immunoglobulin production

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Critical role for IL-15 in innate immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

A potential role for interleukin-15 in the regulation of human natural killer cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemoattraction of human blood T lymphocytes by interleukin-15.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: IL-15 costimulates the generalized Shwartzman reaction and innate immune IFN-gamma production in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Highly efficient gene transfer into murine liver achieved by intravenous administration of naked Epstein-Barr virus (EBV)-based plasmid vectors.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Accumulation of a potent gammadelta T-cell stimulator after deletion of the lytB gene in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-21 is a growth and survival factor for human myeloma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Dissimilar anti-tumour reactions induced by tumour cells engineered with the interleukin-2 or interleukin-15 gene in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 15-mediated induction of cytotoxic effector cells capable of eliminating Epstein-Barr virus-transformed/immortalized lymphocytes in culture.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-12 in anti-tumor immunity and immunotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Significant Antitumor Effects Obtained by Autologous Tumor Cell Vaccine Engineered to Secrete Interleukin (IL)-12 and IL-18 by Means of the EBV/Lipoplex

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-18 and IL-12 induce intestinal inflammation and fatty liver in mice in an IFN-gamma dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Development of catheter-based procedures for transducing the isolated rabbit liver with plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Noninvasive gene delivery to the liver by mechanical massage

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Nonviral genetic transfer of Fas ligand induced significant growth suppression and apoptotic tumor cell death in prostate cancer in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Extremely efficient gene transfection into lympho-hematopoietic cell lines by Epstein-Barr virus-based vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Potent antitumor effects mediated by local expression of the mature form of the interferon-gamma inducing factor, interleukin-18 (IL-18).

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900222-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1525-0016(03)00222-3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14529827%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14529827%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

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