(Q45872463)

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In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells

scientific article published in October 2000

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

Escherichia coli

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Sorscher EJ

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

author name string

Gadi VK

1

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

Alexander SD

2

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

Kudlow JE

3

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

Allan P

4

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

Parker WB

5

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

publication date

1 October 2000

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

7

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

20

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

1738-1743

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

https://scigraph.springernature.com/pub.10.1038/sj.gt.3301286

0 references

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1 reference

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In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase

1 reference

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Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells

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In vivo gene therapy for prostate cancer: preclinical evaluation of two different enzyme-directed prodrug therapy systems delivered by identical adenovirus vectors

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Thymidine kinase-deleted vaccinia virus expressing purine nucleoside phosphorylase as a vector for tumor-directed gene therapy

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Purine Nucleoside Phosphorylase from Escherichia coli and Salmonella typhimurium. Purification and Some Properties

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The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

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Foamy virus vectors for suicide gene therapy

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The thymidine kinase/ganciclovir-mediated "suicide" effect is variable in different tumor cells

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The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro

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Bystander tumoricidal effect and gap junctional communication in lung cancer cell lines.

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Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma

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Gene therapy of rat 9L gliosarcoma tumors by transduction with selectable genes does not require drug selection

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Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

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Gene-Directed Enzyme Prodrug Therapy

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Cell to cell contact is not required for bystander cell killing by Escherichia coli purine nucleoside phosphorylase

1 reference

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7 January 2021

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10.1038/SJ.GT.3301286

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11083495

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