(Q45875289)

17 December 2017

title

Corneal gene delivery: chitosan oligomer as a carrier of CpG rich, CpG free or S/MAR plasmid DNA. (English)

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17 December 2017

author name string

Eytan A Klausner

1

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17 December 2017

Zhong Zhang

2

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17 December 2017

Suet P Wong

3

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17 December 2017

Robert L Chapman

4

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17 December 2017

Michael V Volin

5

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17 December 2017

Richard P Harbottle

6

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17 December 2017

publication date

1 February 2012

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17 December 2017

published in

Journal of Gene Medicine

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17 December 2017

volume

14

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17 December 2017

issue

2

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17 December 2017

page(s)

100-108

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17 December 2017

Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery.

cites work

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Design and development of polymers for gene delivery

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Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes

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Controlling the kinetics of transgene expression by plasmid design

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Muscular gene transfer using nonviral vectors

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Bioadhesive hyaluronan-chitosan nanoparticles can transport genes across the ocular mucosa and transfect ocular tissue

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Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression.

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Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery

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Designing plasmid vectors.

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Characterization of the transgene expression generated by branched and linear polyethylenimine-plasmid DNA nanoparticles in vitro and after intraperitoneal injection in vivo

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Ultrapure chitosan oligomers as carriers for corneal gene transfer

21 January 2018

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Gene therapy progress and prospects: synthetic polymer-based systems.

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Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes.

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The role of CpG motifs in immunostimulation and gene therapy

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CpG motifs in bacterial DNA trigger direct B-cell activation

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Use of minicircle plasmids for gene therapy.

21 January 2018

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The effect of CpG motifs on gene expression and clearance kinetics of aerosol administered polyethylenimine (PEI)-plasmid DNA complexes in the lung

21 January 2018

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CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.

21 January 2018

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Towards safe, non-viral therapeutic gene expression in humans.

21 January 2018

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Optimization of cis-acting elements for gene expression from nonviral vectors in vivo

21 January 2018

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Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.

21 January 2018

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Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency.

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Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

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Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation

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Optimization and delivery of plasmid DNA for vaccination

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Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose

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Immune response induced by a linear DNA vector: influence of dose, formulation and route of injection

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A nonviral minicircle vector for deriving human iPS cells

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Promoter- and strain-selective enhancement of gene expression in a mouse skeletal muscle by a polymer excipient Pluronic P85.

21 January 2018

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Nonviral delivery for genomic therapy of cancer

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Nonviral vectors for gene delivery

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Gene delivery mediated by recombinant silk proteins containing cationic and cell binding motifs

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In vivo electroporation and ubiquitin promoter--a protocol for sustained gene expression in the lung.

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Local and systemic inoculation of DNA or protein gB1s-based vaccines induce a protective immunity against rabbit ocular HSV-1 infection

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21 January 2018

Identifiers

DOI

10.1002/JGM.1634

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17 December 2017

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17 December 2017