(Q45875353)

17 December 2017

title

Alleviation of Abeta-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model (English)

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17 December 2017

main subject

cognitive dysfunction

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S Takeda

5

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author name string

D Takeuchi

1

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17 December 2017

N Sato

2

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17 December 2017

M Shimamura

3

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17 December 2017

H Kurinami

4

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17 December 2017

M Shinohara

6

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17 December 2017

S Suzuki

7

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17 December 2017

M Kojima

8

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17 December 2017

T Ogihara

9

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17 December 2017

R Morishita

10

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17 December 2017

publication date

21 February 2008

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

15

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17 December 2017

issue

8

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17 December 2017

page(s)

561-571

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17 December 2017

In Vivo Activation of met Tyrosine Kinase by Heterodimeric Hepatocyte Growth Factor Molecule Promotes Angiogenesis

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Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

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Translational research on the way to effective therapy for Alzheimer disease

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7 January 2021

Hope for AD with NGF gene-therapy trial

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7 January 2021

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

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7 January 2021

Molecular cloning and expression of human hepatocyte growth factor

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7 January 2021

Expression of c-Met in developing rat hippocampus: evidence for HGF as a neurotrophic factor for calbindin D-expressing neurons

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7 January 2021

Hepatocyte growth factor as an enhancer of nmda currents and synaptic plasticity in the hippocampus

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https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Development of efficient plasmid DNA transfer into adult rat central nervous system using microbubble-enhanced ultrasound

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7 January 2021

Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease

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7 January 2021

Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model

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https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Intrathecal injection of HVJ-E containing HGF gene to cerebrospinal fluid can prevent and ameliorate hearing impairment in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Effects of hepatocyte growth factor on differentiation and cMET receptor expression in the promyelocytic HL60 cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

A humanin derivative, S14G-HN, prevents amyloid-beta-induced memory impairment in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Regional variation in brain capillary density and vascular response to ischemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Cerebrovascular responsiveness to hypercapnia in Alzheimer's dementia and vascular dementia of the Binswanger type

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury

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7 January 2021

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra.

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7 January 2021

BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies

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7 January 2021

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7 January 2021

Age-dependent cerebrovascular abnormalities and blood flow disturbances in APP23 mice modeling Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Apoptotic death in an in vitro model of neuronal oxidative stress.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Oxidative stress signalling in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

HGF promotes survival and growth of maturing sympathetic neurons by PI-3 kinase- and MAP kinase-dependent mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

The protective effect of hepatocyte growth factor against cell death in the hippocampus after transient forebrain ischemia is related to the improvement of apurinic/apyrimidinic endonuclease/redox factor-1 level and inhibition of NADPH oxidase activ

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Inhibition of hypoxia/reoxygenation-induced oxidative stress in HGF-stimulated antiapoptotic signaling: role of PI3-K and Akt kinase upon rac1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

CREB is a regulatory target for the protein kinase Akt/PKB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Comparative evaluation of synaptophysin-based methods for quantification of synapses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Quantitative evaluation of synaptophysin-like immunoreactive nerve terminals or varicosities in anterior pituitary of normal and adrenalectomized rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Stage-dependent BDNF serum concentrations in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Effect of the BDNF V166M polymorphism on working memory in healthy adolescents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Hepatocyte growth factor (HGF/SF) in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Hepatocyte growth factor-induced differential activation of phospholipase cgamma 1 and phosphatidylinositol 3-kinase is regulated by tyrosine phosphatase SHP-1 in astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Long-term deprivation of oestrogens by ovariectomy potentiates beta-amyloid-induced working memory deficits in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

The role of nociceptin in cognition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3303094

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3303094

1 reference

17 December 2017

Dimensions Publication ID

1053518046

0 references

1 reference

17 December 2017