(Q45876450)

17 December 2017

title

Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo (English)

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17 December 2017

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Ghaneh P

1

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17 December 2017

Greenhalf W

2

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17 December 2017

Humphreys M

3

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17 December 2017

Wilson D

4

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17 December 2017

Zumstein L

5

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17 December 2017

Lemoine NR

6

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17 December 2017

Neoptolemos JP

7

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17 December 2017

publication date

1 February 2001

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

8

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17 December 2017

issue

3

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17 December 2017

page(s)

199-208

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3301394

exact match

0 references

cites work

Cancer statistics, 1994.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Regulation of p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

The p53 tumour suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Growth suppression by p16ink4 requires functional retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

The potential for gene therapy in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments]

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Abnormalities of the RB1 and DCC tumor suppressor genes: Uncommon in human pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Overexpression of E2F-1 in glioma triggers apoptosis and suppresses tumor growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Pre-existing immunity to adenovirus does not prevent tumor regression following intratumoral administration of a vector expressing IL-12 but inhibits virus dissemination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

Treatment and survival in 13560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: An epidemiological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

7 January 2021

p16/MTS1/INK4A suppresses prostate cancer by both pRb dependent and independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

7 January 2021

Adenovirus-mediated p53 growth inhibition of ovarian cancer cells is independent of endogenous p53 status

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301394

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301394

1 reference

17 December 2017

Dimensions Publication ID

1008667002

0 references

1 reference

17 December 2017