(Q45885573)

17 December 2017

title

Enhanced tumor suppression by adenoviral PTEN gene therapy combined with cisplatin chemotherapy in small-cell lung cancer (English)

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17 December 2017

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D Li

1

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17 December 2017

Y Zhang

2

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17 December 2017

Y Xie

3

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17 December 2017

J Xiang

4

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17 December 2017

Y Zhu

5

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17 December 2017

J Yang

6

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17 December 2017

publication date

8 March 2013

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17 December 2017

published in

Cancer Gene Therapy

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17 December 2017

volume

20

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17 December 2017

issue

4

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17 December 2017

page(s)

251-259

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/cgt.2013.14

exact match

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cites work

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

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Endogenous viruses: insights into viral evolution and impact on host biology

21 January 2018

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Tenets of PTEN tumor suppression

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Adenovirus-mediated transfer of the PTEN gene inhibits human colorectal cancer growth in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Urocanic acid-modified chitosan-mediated PTEN delivery via aerosol suppressed lung tumorigenesis in K-ras(LA1) mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Loss of PTEN permits CXCR4-mediated tumorigenesis through ERK1/2 in prostate cancer cells

21 January 2018

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In vivo gene therapy of human bladder cancer with PTEN suppresses tumor growth, downregulates phosphorylated Akt, and increases sensitivity to doxorubicin

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Modulation of Akt/mTOR signaling overcomes sunitinib resistance in renal and prostate cancer cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development.

21 January 2018

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Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner

21 January 2018

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The resurgence of platinum-based cancer chemotherapy

21 January 2018

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Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells

21 January 2018

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PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Effect of tumor suppressor gene PTEN on the resistance to cisplatin in human ovarian cancer cell lines and related mechanisms

21 January 2018

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PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers

21 January 2018

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A gene-alteration profile of human lung cancer cell lines.

21 January 2018

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A simplified system for generating recombinant adenoviruses

21 January 2018

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Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Synergistic tumor suppression by adenovirus-mediated inhibitor of growth 4 and interleukin-24 gene cotransfer in hepatocarcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Tumor and host factors that may limit efficacy of chemotherapy in non-small cell and small cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Cell surface tetraspanin CD9 mediates chemoresistance in small cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Two novel determinants of etoposide resistance in small cell lung cancer.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Overcoming cisplatin resistance by mTOR inhibitor in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

21 January 2018

Modes of p53 regulation

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

Mechanistic insights into maintenance of high p53 acetylation by PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

G1 cell-cycle control and cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Cell death: critical control points

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

Survivin, cancer networks and pathway-directed drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

Endogenous tumor suppression mediated by PTEN involves survivin gene silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

PTEN controls tumor-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

Combination of low-dose cisplatin and recombinant xenogeneic endoglin as a vaccine induces synergistic antitumor activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

21 January 2018

Small-cell lung cancer

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https://api.crossref.org/works/10.1038%2FCGT.2013.14

7 January 2021

The functions and regulation of the PTEN tumour suppressor

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

7 January 2021

Suppression of tumorigenicity and metastasis in B16F10 cells by PTEN/MMAC1/TEP1 gene

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

7 January 2021

Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

7 January 2021

A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

7 January 2021

PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2013.14

7 January 2021

Identifiers

DOI

10.1038/CGT.2013.14

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017