(Q45888026)

17 December 2017

title

Tumor-targeted gene delivery of tumor necrosis factor-alpha induces tumor necrosis and tumor regression without systemic toxicity (English)

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17 December 2017

author

Ernst Wagner

8

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17 December 2017

author name string

Ralf Kircheis

1

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17 December 2017

Elinborg Ostermann

2

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17 December 2017

Markus F Wolschek

3

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17 December 2017

Cornelia Lichtenberger

4

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17 December 2017

Christine Magin-Lachmann

5

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17 December 2017

Lionel Wightman

6

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17 December 2017

Malgorzata Kursa

7

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17 December 2017

publication date

1 August 2002

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17 December 2017

published in

Cancer Gene Therapy

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17 December 2017

volume

9

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17 December 2017

issue

8

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17 December 2017

page(s)

673-680

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700487

exact match

0 references

cites work

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PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

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21 January 2018

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Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

21 January 2018

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Cachectin and tumour necrosis factor as two sides of the same biological coin

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A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon

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Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience

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Absence of severe systemic toxicity after leakage-controlled isolated limb perfusion with tumor necrosis factor-alpha and melphalan

21 January 2018

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Polyethylenimine-based intravenous delivery of transgenes to mouse lung.

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LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth

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Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: phase I toxicity and effects on lipid metabolism

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Phase II clinical trial of high-dose recombinant human tumor necrosis factor

21 January 2018

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Microvascular permeability of normal and neoplastic tissues

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Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment

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Early endothelium activation and polymorphonuclear cell invasion precede specific necrosis of human melanoma and sarcoma treated by intravascular high-dose tumour necrosis factor alpha (rTNF alpha)

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7 January 2021

Macroscopic and microscopic early effects of tumour necrosis factor on murine Meth A sarcoma, and relation to curative activity

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7 January 2021

Tumor necrosis factor causes microvascular protein leakage independently of neutrophils or mast cells

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7 January 2021

Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation

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7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700487

1 reference

17 December 2017

Dimensions Publication ID

0 references

1 reference

17 December 2017