(Q45896502)

17 December 2017

title

Oral delivery of siRNA and antisense oligonucleotides (English)

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17 December 2017

author name string

Saghir Akhtar

series ordinal

1

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17 December 2017

publication date

1 August 2009

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17 December 2017

Journal of Drug Targeting

published in

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17 December 2017

volume

17

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17 December 2017

issue

7

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17 December 2017

page(s)

491-495

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17 December 2017

Cellular delivery in vivo of siRNA-based therapeutics

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Toxicogenomics of non-viral drug delivery systems for RNAi: potential impact on siRNA-mediated gene silencing activity and specificity

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The delivery of antisense therapeutics

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Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation

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Gene silencing nucleic acids designed by scanning arrays: anti-EGFR activity of siRNA, ribozyme and DNA enzymes targeting a single hybridization-accessible region using the same delivery system

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Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

21 January 2018

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M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis.

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The promises and pitfalls of RNA-interference-based therapeutics

21 January 2018

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State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers.

21 January 2018

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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Issues in oral nanoparticle drug carrier uptake and targeting

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21 January 2018

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Delivery strategies for siRNA-mediated gene silencing

21 January 2018

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Toxicogenomics of drug delivery systems: Exploiting delivery system-induced changes in target gene expression to enhance siRNA activity

21 January 2018

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The cellular delivery of antisense oligonucleotides and ribozymes

21 January 2018

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Recent advances in the understanding of uptake of microparticulates across the gastrointestinal lymphatics

21 January 2018

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Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

21 January 2018

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Polymer genomics: an insight into pharmacology and toxicology of nanomedicines

21 January 2018

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Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: in vitro and in vivo studies.

21 January 2018

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Activation and regulation of toll-like receptor 9: CpGs and beyond

21 January 2018

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Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

21 January 2018

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21 January 2018

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RNA interference: from basic research to therapeutic applications

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21 January 2018

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Effect of sodium caprate on the intestinal absorption of two modified antisense oligonucleotides in pigs

21 January 2018

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Oral bioavailability and multiple dose tolerability of an antisense oligonucleotide tablet formulated with sodium caprate

21 January 2018

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Drug delivery of siRNA therapeutics: potentials and limits of nanosystems.

21 January 2018

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Oral delivery of antisense oligonucleotides in man.

21 January 2018

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Knocking down barriers: advances in siRNA delivery

21 January 2018

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10.1080/10611860903057674

21 January 2018

Identifiers

DOI

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17 December 2017

PubMed ID

19530907

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17 December 2017