(Q45937177)

18 December 2017

title

Brca1 heterozygous mice have shortened life span and are prone to ovarian tumorigenesis with haploinsufficiency upon ionizing irradiation. (English)

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18 December 2017

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S Furuta

4

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author name string

Y-M Jeng

1

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18 December 2017

S Cai-Ng

2

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18 December 2017

A Li

3

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18 December 2017

H Chew

5

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18 December 2017

P-L Chen

6

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18 December 2017

E-Y-H Lee

7

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18 December 2017

W-H Lee

8

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18 December 2017

language of work or name

English

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publication date

9 April 2007

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18 December 2017

published in

Oncogene

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18 December 2017

volume

26

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18 December 2017

issue

42

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18 December 2017

page(s)

6160-6166

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210451

exact match

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Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform

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Premature aging in mice deficient in DNA repair and transcription

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Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers

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Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

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CBP/p300 interact with and function as transcriptional coactivators of BRCA1

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Relationship between lifetime ovulatory cycles and overexpression of mutant p53 in epithelial ovarian cancer.

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BRCA1 is a component of the RNA polymerase II holoenzyme

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Late toxicity is not increased in BRCA1/BRCA2 mutation carriers undergoing breast radiotherapy in the United Kingdom.

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The BRCT Domain Is a Phospho-Protein Binding Domain

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Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

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Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status

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7 January 2021

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

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7 January 2021

Carcinogenicity of dimethylarsinic acid in p53 heterozygous knockout and wild-type C57BL/6J mice

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7 January 2021

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210451

1 reference

18 December 2017

Dimensions Publication ID

1048892895

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1 reference

18 December 2017