(Q45940050)

18 December 2017

title

TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum. (English)

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18 December 2017

main subject

endoplasmic reticulum

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author

Ramanujan Shankar Hegde

1

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18 December 2017

Tom Rapoport

3

object named as

T A Rapoport

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18 December 2017

author name string

S Voigt

2

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18 December 2017

V R Lingappa

4

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18 December 2017

language of work or name

English

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publication date

1 March 1998

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18 December 2017

published in

Cell

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18 December 2017

volume

92

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18 December 2017

page(s)

621-631

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18 December 2017

issue

5

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18 December 2017

BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum

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Pause transfer: a topogenic sequence in apolipoprotein B mediates stopping and restarting of translocation

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Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore.

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The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process

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The degradation of apolipoprotein B100 is mediated by the ubiquitin-proteasome pathway and involves heat shock protein 70

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Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane

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7 January 2021

Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol

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7 January 2021

A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane

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Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration

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An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

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Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation.

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The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum

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7 January 2021

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

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Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes

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Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane

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7 January 2021

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

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Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins.

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Ubiquitin-proteasome pathway mediates intracellular degradation of apolipoprotein B

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7 January 2021

A protein of the endoplasmic reticulum involved early in polypeptide translocation

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7 January 2021

10.1016/S0092-8674(00)81130-7

Identifiers

DOI

1 reference

18 December 2017

PubMed ID

9506517

1 reference

18 December 2017