(Q45959540)

18 December 2017

title

Association between MGMT promoter hypermethylation and p53 mutation in glioblastoma. (English)

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18 December 2017

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Jamal Shamsara

1

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18 December 2017

Samaneh Sharif

2

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18 December 2017

Sima Afsharnezhad

3

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18 December 2017

Marzieh Lotfi

4

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18 December 2017

Hamid Reza Raziee

5

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18 December 2017

Kamran Ghaffarzadegan

6

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18 December 2017

Afshin Moradi

7

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18 December 2017

Saeed Rahighi

8

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18 December 2017

Javad Behravan

9

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18 December 2017

publication date

1 October 2009

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18 December 2017

published in

Cancer Investigation

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18 December 2017

volume

27

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18 December 2017

issue

8

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18 December 2017

page(s)

825-829

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18 December 2017

Therapeutic advances in the treatment of glioblastoma: rationale and potential role of targeted agents

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Cancer statistics, 2007

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Mutator pathways unleashed by epigenetic silencing in human cancer

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

DNA repair gene O6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

MGMT gene silencing and benefit from temozolomide in glioblastoma

21 January 2018

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Molecular features of adult glioma associated with patient race/ethnicity, age, and a polymorphism in O6-methylguanine-DNA-methyltransferase.

21 January 2018

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p53 as a target for anti-cancer drug development.

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C --> A:T mutations of the TP53 tumor suppressor gene

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

Activity of O(6)-methylguanine-DNA methyltransferase in relation to p53 status and therapeutic response in ovarian cancer

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

MGMT in primary and recurrent human glioblastomas after radiation and chemotherapy and comparison with p53 status and clinical outcome.

21 January 2018

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 January 2018

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Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900902783211

Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07357900902783211

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relationship to aflatoxin B1-DNA adducts and p53 mutation in hepatocellular carcinoma

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

p53 and breast cancer, an update

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

Genetic pathways to primary and secondary glioblastoma

21 January 2018

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https://api.crossref.org/works/10.1080%2F07357900902783211

10.1080/07357900902783211

21 January 2018

Identifiers

DOI

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18 December 2017

1 reference

18 December 2017