(Q45960821)

18 December 2017

title

Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. (English)

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18 December 2017

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J Zhang

1

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18 December 2017

Q Sun

2

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18 December 2017

Z Zhang

3

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18 December 2017

S Ge

4

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18 December 2017

Z-G Han

5

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18 December 2017

W-T Chen

6

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18 December 2017

language of work or name

English

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publication date

13 February 2012

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18 December 2017

published in

Oncogene

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18 December 2017

volume

32

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18 December 2017

issue

1

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18 December 2017

page(s)

61-69

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/onc.2012.28

exact match

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cites work

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The molecular biology of head and neck cancer

21 January 2018

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Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Modulation of microRNA processing by p53

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

p21 stability: linking chaperones to a cell cycle checkpoint

21 January 2018

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Traveling Bax and forth from mitochondria to control apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Mdm2 promotes genetic instability and transformation independent of p53.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

21 January 2018

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Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

21 January 2018

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Proteolytic cleavage of the mdm2 oncoprotein during apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

MicroRNA expression profiles of head and neck squamous cell carcinoma with docetaxel-induced multidrug resistance

21 January 2018

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MicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

The miR-143/145 cluster is a novel transcriptional target of Jagged-1/Notch signaling in vascular smooth muscle cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

21 January 2018

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MicroRNAs and their therapeutic potential for human diseases: microRNAs, miR-143 and -145, function as anti-oncomirs and the application of chemically modified miR-143 as an anti-cancer drug

21 January 2018

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Role of anti-oncomirs miR-143 and -145 in human colorectal tumors

21 January 2018

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miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer

21 January 2018

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MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1

21 January 2018

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Role of miR-143 targeting KRAS in colorectal tumorigenesis.

21 January 2018

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Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1 gene

21 January 2018

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p53 represses c-Myc through induction of the tumor suppressor miR-145

21 January 2018

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MiR-145, a new regulator of the DNA fragmentation factor-45 (DFF45)-mediated apoptotic network

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.28

TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

21 January 2018

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microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia

21 January 2018

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MicroRNA as a Novel Modulator in Head and Neck Squamous Carcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.28

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.28

1 reference

18 December 2017

Dimensions Publication ID

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1 reference

18 December 2017