(Q38343171)

2 September 2017

title

Proteolytic cleavage of the mdm2 oncoprotein during apoptosis (English)

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2 September 2017

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L Chen

1

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2 September 2017

V Marechal

2

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2 September 2017

J Moreau

3

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2 September 2017

A J Levine

4

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2 September 2017

J Chen

5

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2 September 2017

language of work or name

English

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publication date

1 September 1997

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Journal of Biological Chemistry

2 September 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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2 September 2017

volume

272

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2 September 2017

issue

36

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2 September 2017

page(s)

22966-22973

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The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

2 September 2017

cites work

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Amplification of a gene encoding a p53-associated protein in human sarcomas

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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p53 mutations in human cancers

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

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Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

21 January 2018

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Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

21 January 2018

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The p53-mdm-2 autoregulatory feedback loop

21 January 2018

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

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Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway

21 January 2018

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mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

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Interaction between the retinoblastoma protein and the oncoprotein MDM2

21 January 2018

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Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

21 January 2018

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The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes

21 January 2018

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Amplification of MDM2 inhibits MyoD-mediated myogenesis

21 January 2018

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Human ICE/CED-3 protease nomenclature

21 January 2018

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The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

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Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

21 January 2018

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Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

21 January 2018

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

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Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

21 January 2018

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Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

21 January 2018

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Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

21 January 2018

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D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis

21 January 2018

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Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

21 January 2018

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 January 2018

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Mapping of the p53 and mdm-2 interaction domains

21 January 2018

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Suppression of human colorectal carcinoma cell growth by wild-type p53

21 January 2018

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21 January 2018

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p53 functions as a cell cycle control protein in osteosarcomas

21 January 2018

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The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

21 January 2018

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Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif

21 January 2018

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Genetic determinants of p53-induced apoptosis and growth arrest

21 January 2018

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

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Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

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Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis

21 January 2018

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The p53-associated protein MDM2 contains a newly characterized zinc-binding domain called the RING finger

21 January 2018

1 reference

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p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.36.22966

1 reference

release_moupvm6upffh5hflme7nfbclyi

2 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/moupvm6upffh5hflme7nfbclyi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference