(Q45989647)

18 December 2017

title

The cytoprotective effects of the glycoprotein 130 receptor-coupled cytokine, cardiotrophin-1, require activation of NF-kappa B. (English)

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18 December 2017

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R Craig

1

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18 December 2017

M Wagner

2

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18 December 2017

T McCardle

3

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18 December 2017

A G Craig

4

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18 December 2017

C C Glembotski

5

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18 December 2017

language of work or name

English

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publication date

11 July 2001

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18 December 2017

Journal of Biological Chemistry

number of pages

9

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based on heuristic

inferred from page(s)

published in

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18 December 2017

volume

276

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18 December 2017

issue

40

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18 December 2017

page(s)

37621-37629

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18 December 2017

p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system

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Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways

21 January 2018

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Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy

21 January 2018

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Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons.

21 January 2018

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A sweat gland-derived differentiation activity acts through known cytokine signaling pathways.

21 January 2018

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gp130 Cytokine family and bone cells

21 January 2018

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Stimulation of osteoclast differentiation in vitro by mouse oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and interleukin 6: synergy with dexamethasone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Cardiotrophin-1: a novel cytokine and its effects in the heart and other tissues

21 January 2018

1 reference

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Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy

21 January 2018

1 reference

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Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes

21 January 2018

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

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PI3K: downstream AKTion blocks apoptosis

21 January 2018

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Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.

21 January 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

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p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

21 January 2018

1 reference

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Involvement of cardiotrophin-1 in cardiac myocyte-nonmyocyte interactions during hypertrophy of rat cardiac myocytes in vitro.

21 January 2018

1 reference

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Involvement of multiple cis elements in basal- and alpha-adrenergic agonist-inducible atrial natriuretic factor transcription. Roles for serum response elements and an SP-1-like element

21 January 2018

1 reference

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A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression

21 January 2018

1 reference

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

21 January 2018

1 reference

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Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

21 January 2018

1 reference

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Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B

21 January 2018

1 reference

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Signaling mechanisms through gp130: a model of the cytokine system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Signal transduction. How receptors turn Ras on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

IkappaBalpha degradation and nuclear factor-kappaB DNA binding are insufficient for interleukin-1beta and tumor necrosis factor-alpha-induced kappaB-dependent transcription. Requirement for an additional activation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Activation of transcription factor NF-kappaB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Grb2 interaction with MEK-kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

AP-1 function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Intracellular signalling: putting JAKs on the kinase MAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

Cardiotrophin-1 and the role of gp130-dependent signaling pathways in cardiac growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103276200

21 January 2018

Identifiers

DOI

10.1074/JBC.M103276200

1 reference

18 December 2017

PubMed ID

11448959

1 reference

18 December 2017