(Q46021567)

18 December 2017

title

Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event. (English)

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18 December 2017

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3

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18 December 2017

author name string

Catherine A Parr-Sturgess

series ordinal

1

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18 December 2017

David J Rushton

series ordinal

2

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18 December 2017

language of work or name

English

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publication date

1 December 2010

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18 December 2017

number of pages

12

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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18 December 2017

volume

432

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18 December 2017

issue

2

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18 December 2017

page(s)

283-294

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18 December 2017

The "a disintegrin and metalloprotease" (ADAM) family of sheddases: physiological and cellular functions

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Processing of the notch ligand delta by the metalloprotease Kuzbanian

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Proteolytic processing of delta-like 1 by ADAM proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Lipid rafts, cholesterol, and the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Lipid rafts identified as locations of ectodomain shedding mediated by Meltrin beta/ADAM19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

The shedding activity of ADAM17 is sequestered in lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Shedding of collagen XVII ectodomain depends on plasma membrane microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Soluble Jagged 1 represses the function of its transmembrane form to induce the formation of the Src-dependent chord-like phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

A non-transmembrane form of Jagged-1 regulates the formation of matrix-dependent chord-like structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Soluble form of Jagged1: unique product of epithelial keratinocytes and a regulator of keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Soluble Jagged-1 is able to inhibit the function of its multivalent form to induce hematopoietic stem cell self-renewal in a surrogate in vitro assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Notch signaling: emerging molecular targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Measurement of protein using bicinchoninic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

The C-terminal PDZ-ligand of JAGGED1 is essential for cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

A cellular striptease act.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Cytokine secretion via cholesterol-rich lipid raft-associated SNAREs at the phagocytic cup.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100321

21 January 2018

Identifiers

DOI

10.1042/BJ20100321

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18 December 2017

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18 December 2017