(Q46057745)

19 December 2017

title

Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells (English)

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19 December 2017

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6

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19 December 2017

Bernd Schnabl

4

object named as

Bernd Schnabl

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19 December 2017

author name string

Samuele De Minicis

1

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19 December 2017

Ekihiro Seki

2

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19 December 2017

Christoph Oesterreicher

3

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19 December 2017

Robert F Schwabe

5

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19 December 2017

language of work or name

English

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publication date

1 December 2008

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19 December 2017

published in

Hepatology

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19 December 2017

volume

48

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19 December 2017

issue

6

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19 December 2017

page(s)

2016-2026

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19 December 2017

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Liver fibrosis -- from bench to bedside

21 January 2018

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Activation of hepatic stellate cells--a key issue in liver fibrosis

21 January 2018

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Is liver fibrosis reversible?

21 January 2018

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Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.

21 January 2018

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Hypothalamic leptin regulation of energy homeostasis and glucose metabolism

21 January 2018

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The adipocyte as an active participant in energy balance and metabolism

21 January 2018

1 reference

Leptin regulation of the immune response and the immunodeficiency of malnutrition

21 January 2018

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Leptin: a multifunctional hormone

21 January 2018

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Induction of leptin receptor expression in the liver by leptin and food deprivation

21 January 2018

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Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis

21 January 2018

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Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice

21 January 2018

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Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways

21 January 2018

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Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells

21 January 2018

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Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes.

21 January 2018

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NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis

21 January 2018

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NADPH oxidase in the liver: defensive, offensive, or fibrogenic?

21 January 2018

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21 January 2018

NOX in liver fibrosis

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NAD(P)H oxidase plays a crucial role in PDGF-induced proliferation of hepatic stellate cells

21 January 2018

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Signaling pathways involved in human vascular smooth muscle cell proliferation and matrix metalloproteinase-2 expression induced by leptin: inhibitory effect of metformin.

21 January 2018

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Role of extracellular signal-regulated kinases (ERK) in leptin-induced hypertension.

21 January 2018

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Cell-specific Cre-mediated activation of the diphtheria toxin gene in pituitary tumor cells: potential for cytotoxic gene therapy.

21 January 2018

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Fatty acid amide hydrolase determines anandamide-induced cell death in the liver

21 January 2018

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DNase I-hypersensitive sites enhance alpha1(I) collagen gene expression in hepatic stellate cells

21 January 2018

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A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations.

21 January 2018

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Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis.

21 January 2018

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Immortal activated human hepatic stellate cells generated by ectopic telomerase expression

21 January 2018

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Gene expression profiles during hepatic stellate cell activation in culture and in vivo

21 January 2018

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High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase

21 January 2018

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CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells

21 January 2018

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Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells

21 January 2018

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Direct effects of leptin on brown and white adipose tissue

21 January 2018

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Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals

21 January 2018

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Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver

21 January 2018

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Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo

21 January 2018

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Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways

21 January 2018

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Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

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The role of leptin in progression of non-alcoholic fatty liver disease

21 January 2018

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Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways

21 January 2018

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Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation

21 January 2018

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7 January 2021

Leptin, liver, and obese mice--fibrosis in the fat lane

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7 January 2021

Hepatic leptin signaling in obesity.

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7 January 2021

Leptin and liver fibrosis: A matter of fat

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7 January 2021

Time-dependent transition from H(2)O(2)-extracellular signal-regulated kinase- to O(2)-nitric oxide-dependent mechanisms in the stimulatory effect of leptin on renal Na+/K+/-ATPase in the rat

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7 January 2021

Leptin enhances alpha1(I) collagen gene expression in LX-2 human hepatic stellate cells through JAK-mediated H2O2-dependent MAPK pathways

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7 January 2021

Differential role of I kappa B kinase 1 and 2 in primary rat hepatocytes

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7 January 2021

Identifiers

DOI

10.1002/HEP.22560

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19 December 2017

PubMed ID

19025999

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19 December 2017