(Q46083528)

19 December 2017

title

Two pathways for cysteine biosynthesis in Leishmania major (English)

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19 December 2017

cystathionine beta-synthase

main subject

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GeneDB

serine acetyltransferase, putative

5 February 2019

serine acetyltransferase

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6 February 2019

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serine acetyltransferase, putative

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cystathionine beta-synthase (fragment)

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cysteine synthase

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cystathionine beta-synthase

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serine acetyltransferase

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1

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19 December 2017

Gareth D Westrop

series ordinal

2

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19 December 2017

author name string

Graham H Coombs

series ordinal

3

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19 December 2017

language of work or name

English

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publication date

27 May 2009

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19 December 2017

published in

Biochemical Journal

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19 December 2017

volume

420

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19 December 2017

issue

3

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19 December 2017

page(s)

451-462

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19 December 2017

Chemotherapy of leishmaniasis

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Cholesterol: a potential therapeutic target in Leishmania infection?

21 January 2018

1 reference

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Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism

21 January 2018

1 reference

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Characterization of transsulfuration and cysteine biosynthetic pathways in the protozoan hemoflagellate, Trypanosoma cruzi. Isolation and molecular characterization of cystathionine beta-synthase and serine acetyltransferase from Trypanosoma

21 January 2018

1 reference

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Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites

21 January 2018

1 reference

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Thiol-based redox metabolism of protozoan parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Molecular and biochemical analysis of the enzymes of cysteine biosynthesis in the plant Arabidopsis thaliana.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism

21 January 2018

1 reference

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Rapid isolation of DNA from trypanosomatid protozoa using a simple 'mini-prep' procedure.

21 January 2018

1 reference

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The cysteine synthase complex from plants. Mitochondrial serine acetyltransferase from Arabidopsis thaliana carries a bifunctional domain for catalysis and protein-protein interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Studies on the synthesis of the Fe-S cluster of dihydroxy-acid dehydratase in escherichia coli crude extract. Isolation of O-acetylserine sulfhydrylases A and B and beta-cystathionase based on their ability to mobilize sulfur from cysteine and to pa

21 January 2018

1 reference

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Reduction of anti-leishmanial pentavalent antimonial drugs by a parasite-specific thiol-dependent reductase, TDR1.

21 January 2018

1 reference

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Purine nucleobase transport in amastigotes of Leishmania mexicana: involvement in allopurinol uptake

21 January 2018

1 reference

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Complexes of serine acetyltransferase and isozymes of cysteine synthase in spinach leaves

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Subcellular distribution of serine acetyltransferase from Pisum sativum and characterization of an Arabidopsis thaliana putative cytosolic isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

DNA sequences of the cysK regions of Salmonella typhimurium and Escherichia coli and linkage of the cysK regions to ptsH.

21 January 2018

1 reference

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Structure of the O-acetylserine sulfhydrylase isoenzyme CysM from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Three-dimensional structure of a new enzyme, O-phosphoserine sulfhydrylase, involved in l-cysteine biosynthesis by a hyperthermophilic archaeon, Aeropyrum pernix K1, at 2.0A resolution

21 January 2018

1 reference

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Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana

21 January 2018

1 reference

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Mutational analysis of O-acetylserine (thiol) lyase conducted in yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Interactions between serine acetyltransferase and O-acetylserine (thiol) lyase in higher plants--structural and kinetic properties of the free and bound enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Evolutionary relationships among pyridoxal-5'-phosphate-dependent enzymes. Regio-specific alpha, beta and gamma families

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

The role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania major

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Ovothiol and trypanothione as antioxidants in trypanosomatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Leishmania tropica: uptake of methionine by promastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

A mechanistic model of the cysteine synthase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

The active site of O-acetylserine sulfhydrylase is the anchor point for bienzyme complex formation with serine acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Cysteine synthesis in plants: protein-protein interactions of serine acetyltransferase from Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Retooling Leishmania metabolism: from sand fly gut to human macrophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Purification and characterization of the wild type and truncated human cystathionine beta-synthase enzymes expressed in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Cysteine eliminates the feeder cell requirement for cultivation of Trypanosoma brucei bloodstream forms in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Characterization of Trypanosoma cruzi L-cysteine transport mechanisms and their adaptive regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

Biochemical characterization of serine transport in Leishmania (Leishmania) amazonensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20082441

21 January 2018

Identifiers

DOI

10.1042/BJ20082441

1 reference

19 December 2017

1 reference

19 December 2017