(Q46084031)

19 December 2017

title

Reduced in vivo phosphodiesterase-4 response to acute noradrenaline challenge in diet-induced obese rats (English)

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19 December 2017

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19 December 2017

Miran Kenk

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Miran Kenk

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author name string

Michael Greene

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19 December 2017

James T Thackeray

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Stephanie L Thorn

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19 December 2017

Lisa Bevilacqua

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Rob S Beanlands

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19 December 2017

Jean N Dasilva

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19 December 2017

publication date

1 March 2009

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19 December 2017

Canadian Journal of Physiology and Pharmacology

published in

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19 December 2017

volume

87

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19 December 2017

issue

3

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19 December 2017

page(s)

196-202

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19 December 2017

betaAR signaling required for diet-induced thermogenesis and obesity resistance

cites work

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Early alterations in the brown adipose tissue adenylate cyclase system of pre-obese Zucker rat fa/fa pups: decreased G-proteins and beta 3-adrenoceptor activities

21 January 2018

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The beta-adrenergic receptors and the control of adipose tissue metabolism and thermogenesis

21 January 2018

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Expression and regulation of human and rat phosphodiesterase type IV isogenes

21 January 2018

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Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

21 January 2018

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Characterization of diet-induced obese rats that develop persistent obesity after 6 months of high-fat followed by 1 month of low-fat diet

21 January 2018

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Relation of body weight to development of coronary heart disease. The Framingham study

21 January 2018

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In vivo selective binding of (R)-[11C]rolipram to phosphodiesterase-4 provides the basis for studying intracellular cAMP signaling in the myocardium and other peripheral tissues.

21 January 2018

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Conformational difference between PDE4 apoenzyme and holoenzyme

21 January 2018

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Characterization of r-[11C]rolipram for PET imaging of phosphodieterase-4: in vivo binding, metabolism, and dosimetry studies in rats.

21 January 2018

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Increasing synaptic noradrenaline, serotonin and histamine enhances in vivo binding of phosphodiesterase-4 inhibitor (R)-[11C]rolipram in rat brain, lung and heart.

21 January 2018

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Rapid regulation of a cyclic AMP-specific phosphodiesterase (PDE IV) by forskolin and isoproterenol in LRM55 astroglial cells

21 January 2018

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Cyclic nucleotide phosphodiesterase 3 expression in vivo: evidence for tissue-specific expression of phosphodiesterase 3A or 3B mRNA and activity in the aorta and adipose tissue of atherosclerosis-prone insulin-resistant rats

21 January 2018

1 reference

Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Ph

21 January 2018

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Alpha 1- and beta-adrenergic receptors in brown adipose tissue of lean (Fa/?) and obese (fa/fa) Zucker rats. Effects of cold-acclimation, sucrose feeding and adrenalectomy

21 January 2018

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Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

21 January 2018

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Hypothesis: Beta-adrenergic receptor blockers and weight gain: A systematic analysis

21 January 2018

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Differential effects of high-fat and high-carbohydrate isoenergetic meals on cardiac autonomic nervous system activity in lean and obese women

21 January 2018

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PDE 4 inhibitors: the use of molecular cloning in the design and development of novel drugs

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y09-001

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19 December 2017

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19 December 2017