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English
The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes.
scientific article published on 9 March 2009
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
title
The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
main subject
type-1 diabetes
1 reference
based on heuristic
inferred from title
preproinsulin
1 reference
based on heuristic
inferred from title
author
Nicholas A. Williamson
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Eric C. Reynolds
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Neil M O'Brien-Simpson
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Anthony W. Purcell
series ordinal
7
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
Swee Heng Milon Pang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
author name string
S I Mannering
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
G Naselli
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
L C Harrison
series ordinal
8
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
publication date
9 March 2009
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
published in
Clinical and Experimental Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
volume
156
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
page(s)
226-231
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
cites work
Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1111%2FJ.1365-2249.2009.03907.X
retrieved
21 January 2018
Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1111%2FJ.1365-2249.2009.03907.X
retrieved
21 January 2018
T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
retrieved
3 November 2018
Insulin as an autoantigen in NOD/human diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
retrieved
3 November 2018
DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
The insulin A-chain epitope recognized by human T cells is posttranslationally modified
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
retrieved
3 November 2018
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
An efficient method for cloning human autoantigen-specific T cells.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
A sensitive method for detecting proliferation of rare autoantigen-specific human T cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Proinsulin-a pathogenic autoantigen in type 1 diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Genes and cellular requirements for autoimmune diabetes susceptibility in nonobese diabetic mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Cloned T cells from a recent onset IDDM patient reactive with insulin B-chain.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
The role of assembly in insulin's biosynthesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Expression, purification and characterization of recombinant human proinsulin
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Disproportionately elevated proinsulin levels precede the onset of insulin-dependent diabetes mellitus in siblings with low first phase insulin responses. The Childhood Diabetes in Finland Study Group.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Excessive secretion of insulin precursors characterizes and predicts gestational diabetes.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Identification of the type 2 proinsulin processing endopeptidase as PC2, a member of the eukaryote subtilisin family.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
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3 November 2018
Recent insights into CD4+T-cell specificity and function in Type 1 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2759469
retrieved
1 December 2018
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19292763
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1111/J.1365-2249.2009.03907.X
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
PMCID
2759469
0 references
PubMed ID
19292763
1 reference
stated in
Europe PubMed Central
PubMed ID
19292763
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19292763%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
ResearchGate publication ID
24206902
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