(Q46089532)

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Biochemical characterization of GSK1070916, a potent and selective inhibitor of Aurora B and Aurora C kinases with an extremely long residence time1.

scientific article published on 13 May 2009

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19284385

Biochemical characterization of GSK1070916, a potent and selective inhibitor of Aurora B and Aurora C kinases with an extremely long residence time1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19284385

author name string

Kelly Anderson

1

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Zhihong Lai

2

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Octerloney B McDonald

3

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Europe PubMed Central

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19 December 2017

http://europepmc.org/abstract/MED/19284385

J Darren Stuart

4

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Eldridge N Nartey

5

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Mary Ann Hardwicke

6

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Ken Newlander

7

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Dashyant Dhanak

8

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Jerry Adams

9

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Denis Patrick

10

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Robert A Copeland

11

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Peter J Tummino

12

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19 December 2017

http://europepmc.org/abstract/MED/19284385

Jingsong Yang

13

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19 December 2017

http://europepmc.org/abstract/MED/19284385

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publication date

13 May 2009

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19284385

Biochemical Journal

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19 December 2017

http://europepmc.org/abstract/MED/19284385

420

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19 December 2017

http://europepmc.org/abstract/MED/19284385

2

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PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19284385

259-265

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19284385

The Aurora kinases: role in cell transformation and tumorigenesis

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Aurora kinases: shining lights on the therapeutic horizon?

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

The cellular geography of aurora kinases

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Aurora C is directly associated with Survivin and required for cytokinesis.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Structural basis of Aurora-A activation by TPX2 at the mitotic spindle

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Modulation of kinase-inhibitor interactions by auxiliary protein binding: crystallography studies on Aurora A interactions with VX-680 and with TPX2

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B Kinase stimulates Aurora B kinase activity

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Mechanism of Aurora B activation by INCENP and inhibition by hesperadin

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

The catalytic role of INCENP in Aurora B activation and the kinetic mechanism of Aurora B/INCENP.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Aurora kinases, aneuploidy and cancer, a coincidence or a real link?

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Aurora kinase inhibitors: a new class of targeted drugs in cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Progress in the development of selective inhibitors of Aurora kinases

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Optimal Sox-based fluorescent chemosensor design for serine/threonine protein kinases.

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Imaging systems in assay screening

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Immobilized metal ion affinity-based fluorescence polarization (IMAP): advances in kinase screening

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Mechanism of time-dependent inhibition of polypeptide deformylase by actinonin

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Drug-target residence time and its implications for lead optimization

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Residence time of receptor-ligand complexes and its effect on biological function

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090121

21 January 2018

Identifiers

10.1042/BJ20090121

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19284385

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19284385

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