(Q46118539)

English

Locally increased P-glycoprotein function in major depression: a PET study with [11C]verapamil as a probe for P-glycoprotein function in the blood-brain barrier

scientific article published on 19 February 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

Locally increased P-glycoprotein function in major depression: a PET study with [11C]verapamil as a probe for P-glycoprotein function in the blood-brain barrier (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

blood–brain barrier

1 reference

based on heuristic

inferred from title

author name string

Onno L de Klerk

1

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

Antoon T M Willemsen

2

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

Meyke Roosink

3

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

Anna L Bartels

4

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

N Harry Hendrikse

5

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

Fokko J Bosker

6

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

Johan A den Boer

7

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

publication date

19 February 2009

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

The International Journal of Neuropsychopharmacology

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

12

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

7

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

895-904

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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Venlafaxine induces P-glycoprotein in human Caco-2 cells.

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Cytokines and major depression

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Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression

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Prefrontal cortical-amygdalar metabolism in major depression

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Imaging P-glycoprotein transport activity at the human blood-brain barrier with positron emission tomography

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Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues

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Cytokines sing the blues: inflammation and the pathogenesis of depression

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Prefrontal-subcortical and limbic circuit mediation of major depressive disorder

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MDR1 gene polymorphism in Japanese patients with schizophrenia and mood disorders including depression

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Modulation of p-glycoprotein transport function at the blood-brain barrier

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Fluoxetine inhibits multidrug resistance extrusion pumps and enhances responses to chemotherapy in syngeneic and in human xenograft mouse tumor models

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Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients

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Astroglial expression of the P-glycoprotein is controlled by intracellular CNTF.

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Measurement of striatal and extrastriatal dopamine D1 receptor binding potential with [11C]NNC 112 in humans: validation and reproducibility.

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Cytokine regulation of P-glycoprotein

1 reference

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Depression, II: localization of pathophysiology

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Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation

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Hippocampal volume and depression: a meta-analysis of MRI studies

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Evaluation of tracer kinetic models for quantification of P-glycoprotein function using (R)-[11C]verapamil and PET.

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Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases

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Role of multidrug transporters in pharmacoresistance to antiepileptic drugs

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Pharmacoresistance in epilepsy: a pilot PET study with the P-glycoprotein substrate R-[(11)C]verapamil

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ABCB1 (P-glycoprotein/MDR1) gene G2677T/a sequence variation (polymorphism): lack of association with side effects and therapeutic response in depressed inpatients treated with amitriptyline

1 reference

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7 January 2021

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Blood-brain barrier dysfunction in parkinsonian midbrain in vivo

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Multidrug resistance P-glycoprotein hampers the access of cortisol but not of corticosterone to mouse and human brain

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The role of MDR1 genetic polymorphisms in interindividual variability in P-glycoprotein expression and function

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Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

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Interaction of antiepileptic drugs with human P-glycoprotein in vitro

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Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography

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Inhibition of P-glycoprotein by newer antidepressants

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An improved method for the preparation of [11C]verapamil

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Inhibition of P-glycoprotein function by several antidepressants may not contribute to clinical efficacy

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Blood-cerebrospinal fluid barrier dysfunction for high molecular weight proteins in Alzheimer disease and major depression: indication for disease subsets.

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Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain

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A rating scale for depression

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Evaluation of the role of P-glycoprotein in inflammation induced blood-brain barrier damage

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PET Studies on P-glycoprotein function in the blood-brain barrier: how it affects uptake and binding of drugs within the CNS.

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Analysis of MDR1 haplotypes in Parkinson's disease in a white population.

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Multidrug-resistance protein 1 in focal cortical dysplasia.

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Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds--implications for pharmacokinetics of selected substrates

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Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy

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Clinical aspects of the MDR1 (ABCB1) gene polymorphism

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High association of anticardiolipin antibodies with psychosis

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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Identifiers

10.1017/S1461145709009894

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/19224656

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