(Q46119099)

19 December 2017

title

Role of hepatic transporters in the disposition and hepatotoxicity of a HER2 tyrosine kinase inhibitor CP-724,714. (English)

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19 December 2017

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Bo Feng

1

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19 December 2017

Jinghai J Xu

2

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19 December 2017

Yi-An Bi

3

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19 December 2017

Rouchelle Mireles

4

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19 December 2017

Ralph Davidson

5

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19 December 2017

David B Duignan

6

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19 December 2017

Scott Campbell

7

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19 December 2017

Vsevolod E Kostrubsky

8

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19 December 2017

Margaret C Dunn

9

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19 December 2017

Arthur R Smith

10

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19 December 2017

Huifen F Wang

11

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19 December 2017

publication date

17 February 2009

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19 December 2017

published in

Toxicological Sciences

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19 December 2017

volume

108

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19 December 2017

issue

2

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19 December 2017

page(s)

492-500

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19 December 2017

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Pharmacokinetics of a HER2 tyrosine kinase inhibitor CP-724,714 in patients with advanced malignant HER2 positive solid tumors: correlations with clinical characteristics and safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Transporters and drug discovery: why, when, and how.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Transport, Metabolism, and Hepatotoxicity of Flutamide, Drug–Drug Interaction with Acetaminophen Involving Phase I and Phase II Metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

The organic anion transporter (OATP) family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

First study of the safety, tolerability, and pharmacokinetics of CP-724,714 in patients with advanced malignant solid HER2-expressing tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Hepatobiliary transporters and drug-induced cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Transporters as a determinant of drug clearance and tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

BSEP: function and role in progressive familial intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

A 96-well efflux assay to identify ABCG2 substrates using a stably transfected MDCK II cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

Cellular imaging predictions of clinical drug-induced liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFP033

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFP033

1 reference

19 December 2017

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19 December 2017