(Q46119530)

19 December 2017

title

C. elegans VAB-8 and UNC-73 regulate the SAX-3 receptor to direct cell and growth-cone migrations (English)

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19 December 2017

Protein sax-3 CELE_ZK377.2

main subject

Caenorhabditis elegans

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1 reference

GOA release 2020-03-11

author name string

Natsuko Watari-Goshima

1

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19 December 2017

Ken-ichi Ogura

2

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19 December 2017

Fred W Wolf

3

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19 December 2017

Yoshio Goshima

4

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19 December 2017

Gian Garriga

5

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19 December 2017

language of work or name

English

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publication date

21 January 2007

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19 December 2017

published in

Nature Neuroscience

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19 December 2017

volume

10

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19 December 2017

issue

2

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19 December 2017

page(s)

169-176

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19 December 2017

https://scigraph.springernature.com/pub.10.1038/nn1834

exact match

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cites work

Molecular mechanisms of axon guidance

1 reference

The molecular biology of axon guidance

21 January 2018

1 reference

UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues

21 January 2018

1 reference

Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans.

21 January 2018

1 reference

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

21 January 2018

1 reference

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

21 January 2018

1 reference

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

21 January 2018

1 reference

frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance.

21 January 2018

1 reference

Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons.

21 January 2018

1 reference

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

21 January 2018

1 reference

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

21 January 2018

1 reference

Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex

21 January 2018

1 reference

The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons

21 January 2018

1 reference

Comm sorts robo to control axon guidance at the Drosophila midline.

21 January 2018

1 reference

Comm function in commissural axon guidance: cell-autonomous sorting of Robo in vivo.

21 January 2018

1 reference

Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling

21 January 2018

1 reference

Multiple Wnts and frizzled receptors regulate anteriorly directed cell and growth cone migrations in Caenorhabditis elegans

21 January 2018

1 reference

vab-8 is a key regulator of posteriorly directed migrations in C. elegans and encodes a novel protein with kinesin motor similarity

21 January 2018

1 reference

VAB-8, UNC-73 and MIG-2 regulate axon polarity and cell migration functions of UNC-40 in C. elegans

21 January 2018

1 reference

Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans

21 January 2018

1 reference

The Structure of the Nervous System of the Nematode Caenorhabditis elegans

21 January 2018

1 reference

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

21 January 2018

1 reference

Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila

21 January 2018

1 reference

UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.

21 January 2018

1 reference

A RHO GTPase-mediated pathway is required during P cell migration in Caenorhabditis elegans

21 January 2018

1 reference

The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharynx pumping and normal neurotransmission in C. elegans

21 January 2018

1 reference

CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis

21 January 2018

1 reference

C. elegans slit acts in midline, dorsal-ventral, and anterior-posterior guidance via the SAX-3/Robo receptor.

21 January 2018

1 reference

The conserved immunoglobulin superfamily member SAX-3/Robo directs multiple aspects of axon guidance in C. elegans.

21 January 2018

1 reference

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion

21 January 2018

1 reference

Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function

21 January 2018

1 reference

Mutations affecting embryonic cell migrations in Caenorhabditis elegans

21 January 2018

1 reference

Sensitized genetic backgrounds reveal a role for C. elegans FGF EGL-17 as a repellent for migrating CAN neurons

21 January 2018

1 reference

Slit Stimulation Recruits Dock and Pak to the Roundabout Receptor and Increases Rac Activity to Regulate Axon Repulsion at the CNS Midline

21 January 2018

1 reference

Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion

21 January 2018

1 reference

The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM.

21 January 2018

1 reference

Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons

21 January 2018

1 reference

Regulation of receptor-mediated endocytosis by Rho and Rac.

21 January 2018

1 reference

Selective alterations in biosynthetic and endocytic protein traffic in Madin-Darby canine kidney epithelial cells expressing mutants of the small GTPase Rac1.

21 January 2018

1 reference

Rac recruits high-affinity integrin alphavbeta3 to lamellipodia in endothelial cell migration

21 January 2018

1 reference

The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila

21 January 2018

1 reference

The autophagy-related kinase UNC-51 and its binding partner UNC-14 regulate the subcellular localization of the Netrin receptor UNC-5 in Caenorhabditis elegans

21 January 2018

1 reference

The conserved kinase UNC-51 acts with VAB-8 and UNC-14 to regulate axon outgrowth in C. elegans

21 January 2018

1 reference

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NN1834

1 reference

19 December 2017

Dimensions Publication ID

1036589195

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1 reference

19 December 2017