(Q46146557)

19 December 2017

title

Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure (English)

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19 December 2017

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Akihito Ohta

1

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19 December 2017

Tatemitsu Rai

2

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19 December 2017

Naofumi Yui

3

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19 December 2017

Motoko Chiga

4

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19 December 2017

Sung-Sen Yang

5

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19 December 2017

Shih-Hua Lin

6

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19 December 2017

Eisei Sohara

7

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19 December 2017

Sei Sasaki

8

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19 December 2017

Shinichi Uchida

9

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19 December 2017

publication date

24 July 2009

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19 December 2017

published in

Human Molecular Genetics

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19 December 2017

volume

18

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19 December 2017

issue

20

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19 December 2017

page(s)

3978-3986

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19 December 2017

Syndrome of hypertension and hyperkalemia with normal glomerular filtration rate

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP344

Mineralocorticoid-resistant renal hyperkalemia without salt wasting (type II pseudohypoaldosteronism): role of increased renal chloride reabsorption.

21 January 2018

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Phenotypic and genetic heterogeneity of familial hyperkalaemic hypertension (Gordon syndrome).

21 January 2018

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Human hypertension caused by mutations in WNK kinases

21 January 2018

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Pseudohypoaldosteronism type II: marked sensitivity to thiazides, hypercalciuria, normomagnesemia, and low bone mineral density

21 January 2018

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WNK kinases regulate thiazide-sensitive Na-Cl cotransport

21 January 2018

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Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

21 January 2018

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WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDP344

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDP344

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP344

Regulation of apical localization of the thiazide-sensitive NaCl cotransporter by WNK4 in polarized epithelial cells

21 January 2018

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The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway

21 January 2018

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Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

21 January 2018

1 reference

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WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP344

The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

21 January 2018

1 reference

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WNK kinases and renal sodium transport in health and disease: an integrated view

21 January 2018

1 reference

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WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis

21 January 2018

1 reference

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The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex

21 January 2018

1 reference

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Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

21 January 2018

1 reference

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Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation

21 January 2018

1 reference

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A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission.

21 January 2018

1 reference

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Comparison of simultaneous measurement of mouse systolic arterial blood pressure by radiotelemetry and tail-cuff methods

21 January 2018

1 reference

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Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP344

21 January 2018

Identifiers

DOI

10.1093/HMG/DDP344

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19 December 2017

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19 December 2017