(Q46190805)

20 December 2017

title

17beta-Estradiol modulates apoptosis in pancreatic beta-cells by specific involvement of the sulfonylurea receptor (SUR) isoform SUR1. (English)

1 reference

20 December 2017

5

Almut Grenz

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20 December 2017

3

Hartmut Osswald

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20 December 2017

author name string

Stefanie Ackermann

1

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20 December 2017

Sabrina Hiller

2

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20 December 2017

Martina Lösle

4

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20 December 2017

Annette Hambrock

6

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20 December 2017

language of work or name

English

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publication date

18 December 2008

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20 December 2017

Journal of Biological Chemistry

published in

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20 December 2017

volume

284

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20 December 2017

issue

8

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20 December 2017

page(s)

4905-4913

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20 December 2017

ABCC8 and ABCC9: ABC transporters that regulate K+ channels

cites work

1 reference

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Glibenclamide-induced apoptosis is specifically enhanced by expression of the sulfonylurea receptor isoform SUR1 but not by expression of SUR2B or the mutant SUR1(M1289T).

21 January 2018

1 reference

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Resveratrol binds to the sulfonylurea receptor (SUR) and induces apoptosis in a SUR subtype-specific manner

21 January 2018

1 reference

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Mechanisms linking obesity to insulin resistance and type 2 diabetes

21 January 2018

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The replication of beta cells in normal physiology, in disease and for therapy

21 January 2018

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Preservation of beta-cell function by targeting beta-cell mass

21 January 2018

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Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

21 January 2018

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

21 January 2018

1 reference

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What is gestational diabetes?

21 January 2018

1 reference

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Gestational diabetes: a review of the current literature and guidelines

21 January 2018

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Recurrence of gestational diabetes mellitus: a systematic review

21 January 2018

1 reference

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Novel players in pancreatic islet signaling: from membrane receptors to nuclear channels.

21 January 2018

1 reference

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Effect of 17beta-estradiol on insulin secretion and cytosolic calcium in Min6 mouse insulinoma cells and human islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

The molecular basis of the specificity of action of K(ATP) channel openers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes

21 January 2018

1 reference

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Activating mutations in the ABCC8 gene in neonatal diabetes mellitus

21 January 2018

1 reference

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Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

The mutation Y1206S increases the affinity of the sulphonylurea receptor SUR2A for glibenclamide and enhances the effects of coexpression with Kir6.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Potassium channel openers require ATP to bind to and act through sulfonylurea receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Therapeutic approaches to preserve islet mass in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donors

21 January 2018

1 reference

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17beta-Estradiol protects isolated human pancreatic islets against proinflammatory cytokine-induced cell death: molecular mechanisms and islet functionality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Estrogen and exercise may enhance beta-cell function and mass via insulin receptor substrate 2 induction in ovariectomized diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

17beta-estradiol affects proliferation and apoptosis of rat prostatic smooth muscle cells by modulating cell cycle transition and related proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Estradiol reverses TGF-beta1-induced mesangial cell apoptosis by a casein kinase 2-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Aging correlates with decreased beta-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for Fas and pancreatic duodenal homeobox-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Estrone Sulfate, Estrone, Estradiol and Estriol Plasma Levels in Human Pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Rapid regulation of pancreatic alpha- and beta- cell signalling systems by estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Rapid endocrine disruption: environmental estrogen actions triggered outside the nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Estrogens cross-talk to alpha1b-adrenergic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Insulin secretion and clearance after subacute estradiol administration in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

Oestrogens and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807638200

21 January 2018

Identifiers

DOI

10.1074/JBC.M807638200

1 reference

20 December 2017

1 reference

20 December 2017