(Q46196513)

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Phosphorylation of eIF2α is dispensable for differentiation but required at a posttranscriptional level for paneth cell function and intestinal homeostasis in mice

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

Phosphorylation of eIF2α is dispensable for differentiation but required at a posttranscriptional level for paneth cell function and intestinal homeostasis in mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

phosphorylation

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author name string

Stewart S Cao

1

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

Miao Wang

2

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

Jane C Harrington

3

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

Brandy-Mengchieh Chuang

4

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

Lars Eckmann

5

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

Randal J Kaufman

6

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

publication date

1 April 2014

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

Inflammatory Bowel Diseases

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

20

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

4

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

712-722

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

The unfolded protein response: from stress pathway to homeostatic regulation

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

The impact of the unfolded protein response on human disease

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Coping with stress: eIF2 kinases and translational control

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Unfolded protein response.

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

The multifaceted Paneth cell

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Homeostasis and inflammation in the intestine

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity.

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

The interplay between endoplasmic reticulum stress and inflammation.

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Intestinal homeostasis and its breakdown in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

PKR protects colonic epithelium against colitis through the unfolded protein response and prosurvival signaling

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Translational inhibition of colonic epithelial heat shock proteins by IFN-gamma and TNF-alpha in intestinal inflammation

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Altered endoplasmic reticulum stress affects translation in inactive colon tissue from patients with ulcerative colitis

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Notch: architect, landscaper, and guardian of the intestine

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response.

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Activation of PERK signaling attenuates Abeta-mediated ER stress

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Targeting endoplasmic reticulum stress in metabolic disease

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

The dsRNA protein kinase PKR: virus and cell control

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Inhibition of translational initiation by activators of the glucose-regulated stress protein and heat shock protein stress response systems. Role of the interferon-inducible double-stranded RNA-activated eukaryotic initiation factor 2alpha kinase

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Endoplasmic reticulum stress and inflammation

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

1 reference

https://api.crossref.org/works/10.1097%2FMIB.0000000000000010

21 January 2018

Identifiers

10.1097/MIB.0000000000000010

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

release_dcadlgxg7fcehkrzxjun43ocqm

1 reference

https://api.fatcat.wiki/v0/release/dcadlgxg7fcehkrzxjun43ocqm

24 November 2022

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24577114

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