(Q46215033)

English

DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid

scientific article published in March 2014

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

Tammie S MacFie

1

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Richard Poulsom

2

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Alexandra Parker

3

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Gary Warnes

4

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Tatjana Boitsova

5

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Anke Nijhuis

6

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Nirosha Suraweera

7

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Angela Poehlmann

8

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Jaroslaw Szary

9

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Roger Feakins

10

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Rosemary Jeffery

11

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Richart W Harper

12

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Adrian M Jubb

13

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

James O Lindsay

14

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Andrew Silver

15

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

publication date

1 March 2014

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Inflammatory Bowel Diseases

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

20

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

3

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

514-524

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Cancer surveillance in longstanding ulcerative colitis: endoscopic appearances help predict cancer risk.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: current management

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Chemoprevention of colorectal cancer in ulcerative colitis

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Mesalamine protects against colorectal cancer in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Science funding: Provocative questions in cancer research

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cells

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Mesalazine causes a mitotic arrest and induces caspase-dependent apoptosis in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

The influence of 5-aminosalicylic acid on the progression of colorectal adenomas via the β-catenin signaling pathway

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Genomic instability is an early event during the progression pathway of ulcerative-colitis-related neoplasia

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Role of oxidatively induced DNA lesions in human pathogenesis

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Dual oxidase2 is expressed all along the digestive tract

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Genome-wide transcriptomic analysis of intestinal tissue to assess the impact of nutrition and a secondary nematode challenge in lactating rats.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Dual oxidase in mucosal immunity and host-microbe homeostasis

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Deciphering of the Dual oxidase (Nox family) gene from kuruma shrimp, Marsupenaeus japonicus: full-length cDNA cloning and characterization

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Dual oxidase 2 and glutathione peroxidase gene expression are elevated in hyperimmunized sheep challenged with Haemonchus contortus.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Mechanism of oxidative DNA damage repair and relevance to human pathology

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Role of H2O2 in RET/PTC1 chromosomal rearrangement produced by ionizing radiation in human thyroid cells

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Loss of CDX1 expression in colorectal carcinoma: promoter methylation, mutation, and loss of heterozygosity analyses of 37 cell lines

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: comparison of intraluminal colonic concentrations, serum values, and urinary excretion

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

5-aminosalicylic acid enhances anchorage-independent colorectal cancer cell death.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Inhibition of cell proliferation and invasion in a human colon cancer cell line by 5-aminosalicylic acid

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

The position of the amino group on the benzene ring is critical for mesalamine's improvement of replication fidelity.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

5-aminosalicylic acid interferes in the cell cycle of colorectal cancer cells and induces cell death modes

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

All-trans retinoic acid mediates DUOX2 expression and function in respiratory tract epithelium

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Characterization of epithelial IL-8 response to inflammatory bowel disease mucosal E. coli and its inhibition by mesalamine.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Up-regulation and sustained activation of Stat1 are essential for interferon-gamma (IFN-gamma)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Ce-Duox1/BLI-3 generates reactive oxygen species as a protective innate immune mechanism in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

A direct role for dual oxidase in Drosophila gut immunity

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

A temporal shift in regulatory networks and pathways in the bovine small intestine during Cooperia oncophora infection

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Dual oxidases control release of hydrogen peroxide by the gastric epithelium to prevent Helicobacter felis infection and inflammation in mice

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

New mediators of immunity and inflammation in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Differential gene expression between flat adenoma and normal mucosa in the colon in a microarray analysis

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Colorectal cancer chemoprevention by mesalazine and its derivatives.

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

5-aminosalicylic acid is not protective against colorectal cancer in inflammatory bowel disease: a meta-analysis of non-referral populations

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Targeting NADPH oxidases for the treatment of cancer and inflammation

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Repeated H2 O2 exposure drives cell cycle progression in an in vitro model of ulcerative colitis

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Oxidative DNA damage in the mucosa of ulcerative colitis increases with disease duration and dysplasia

1 reference

https://api.crossref.org/works/10.1097%2F01.MIB.0000442012.45038.0E

21 January 2018

Identifiers

10.1097/01.MIB.0000442012.45038.0E

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24492313

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46215033&oldid=2100055443"