(Q46215753)

1 July 2019

title

SR-B1: A Unique Multifunctional Receptor for Cholesterol Influx and Efflux (English)

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1 July 2019

author

Fredric B Kraemer

series ordinal

3

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1 July 2019

author name string

Wen-Jun Shen

series ordinal

1

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1 July 2019

Salman Azhar

series ordinal

2

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1 July 2019

publication date

10 November 2017

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1 July 2019

Annual Review of Physiology

published in

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1 July 2019

volume

80

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1 July 2019

page(s)

95-116

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1 July 2019

Receptor mediated uptake of paclitaxel from a synthetic high density lipoprotein nanocarrier

cites work

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12 December 2020

SR-B1 and PDZK1: partners in HDL regulation

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12 December 2020

The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids

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12 December 2020

Scavenger receptor BI modulates platelet reactivity and thrombosis in dyslipidemia

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12 December 2020

Regulation by adrenocorticotropic hormone of the in vivo expression of scavenger receptor class B type I (SR-BI), a high density lipoprotein receptor, in steroidogenic cells of the murine adrenal gland

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12 December 2020

High-density lipoprotein as a potential carrier for delivery of a lipophilic antitumoral drug into hepatoma cells

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12 December 2020

A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila

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12 December 2020

Induction of adrenal scavenger receptor BI and increased high density lipoprotein-cholesteryl ether uptake by in vivo inhibition of hepatic lipase

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12 December 2020

Biomimetic, synthetic HDL nanostructures for lymphoma

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12 December 2020

Recombinant HDL-Like Nanoparticles: A Specific Contrast Agent for MRI of Atherosclerotic Plaques

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12 December 2020

Hormonal regulation of adrenal microvillar channel formation

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12 December 2020

Major lipids, apolipoproteins, and risk of vascular disease

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12 December 2020

Abnormal lipoprotein metabolism and reversible female infertility in HDL receptor (SR-BI)-deficient mice

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12 December 2020

MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells

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12 December 2020

Regulation of expression and function of scavenger receptor class B, type I (SR-BI) by Na+/H+ exchanger regulatory factors (NHERFs)

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12 December 2020

HDL as a drug and nucleic acid delivery vehicle

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12 December 2020

Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells

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12 December 2020

Expression and microvillar localization of scavenger receptor, class B, type I (a high density lipoprotein receptor) in luteinized and hormone-desensitized rat ovarian models

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12 December 2020

Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake

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12 December 2020

Cellular cholesterol trafficking and compartmentalization

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12 December 2020

ACTH Regulation of Adrenal SR-B1

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12 December 2020

Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse

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12 December 2020

The Genotype-Tissue Expression (GTEx) Project

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12 December 2020

Consequences of over-expression of rat Scavenger Receptor, SR-BI, in an adrenal cell model

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12 December 2020

Lipoproteins as potential site-specific delivery systems for diagnostic and therapeutic agents

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12 December 2020

Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI

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12 December 2020

Isolation, characterization, and cDNA sequence of a carotenoid binding protein from the silk gland of Bombyx mori larvae

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12 December 2020

Pregnane X receptor-agonists down-regulate hepatic ATP-binding cassette transporter A1 and scavenger receptor class B type I.

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12 December 2020

Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths

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12 December 2020

Negatively cooperative binding of high-density lipoprotein to the HDL receptor SR-BI

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12 December 2020

Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles

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12 December 2020

Identification, primary structure, and distribution of CLA-1, a novel member of the CD36/LIMPII gene family

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12 December 2020

High-density lipoprotein-based contrast agents for multimodal imaging of atherosclerosis.

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12 December 2020

Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein.

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12 December 2020

Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver

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12 December 2020

The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems

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12 December 2020

Assignment of disulfide bridges in bovine CD36.

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12 December 2020

Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat.

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12 December 2020

Adrenal neutral cholesteryl ester hydrolase: identification, subcellular distribution, and sex differences

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12 December 2020

Human apolipoprotein A-I is associated with dengue virus and enhances virus infection through SR-BI.

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12 December 2020

The efficient cellular uptake of high density lipoprotein lipids via scavenger receptor class B type I requires not only receptor-mediated surface binding but also receptor-specific lipid transfer mediated by its extracellular domain

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12 December 2020

Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice

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12 December 2020

Fungal pathogen recognition by scavenger receptors in nematodes and mammals

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12 December 2020

Scavenger receptor B1 is a potential biomarker of human nasopharyngeal carcinoma and its growth is inhibited by HDL-mimetic nanoparticles.

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12 December 2020

Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones

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12 December 2020

Dimerization of the scavenger receptor class B type I: formation, function, and localization in diverse cells and tissues

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12 December 2020

Expression cloning of SR-BI, a CD36-related class B scavenger receptor

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12 December 2020

Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis

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12 December 2020

Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity

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12 December 2020

A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

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12 December 2020

Contributions of a disulfide bond and a reduced cysteine side chain to the intrinsic activity of the high-density lipoprotein receptor SR-BI.

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12 December 2020

Expression of scavenger receptor BI in COS-7 cells alters cholesterol content and distribution

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12 December 2020

Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice

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12 December 2020

Roles of scavenger receptor BI and APO A-I in selective uptake of HDL cholesterol by adrenal cells

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12 December 2020

Hepatitis C virus cell entry: role of lipoproteins and cellular receptors

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12 December 2020

Signalling pathway involving GULP, MAPK and Rac1 for SR-BI-induced phagocytosis of apoptotic cells

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12 December 2020

A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity.

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12 December 2020

A quantitative analysis of apolipoprotein binding to SR-BI: multiple binding sites for lipid-free and lipid-associated apolipoproteins

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12 December 2020

High scavenger receptor class B type I expression is related to tumor aggressiveness and poor prognosis in breast cancer

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12 December 2020

The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence.

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12 December 2020

Alternative forms of the scavenger receptor BI (SR-BI).

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12 December 2020

Lipid droplets and steroidogenic cells.

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12 December 2020

Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A.

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12 December 2020

Regulation of adrenal scavenger receptor-BI expression by ACTH and cellular cholesterol pools

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12 December 2020

A mutant high-density lipoprotein receptor inhibits proliferation of human breast cancer cells

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12 December 2020

Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles

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12 December 2020

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport

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12 December 2020

Targeted Disruption of the PDZK1 Gene in Mice Causes Tissue-specific Depletion of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I and Altered Lipoprotein Metabolism

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12 December 2020

Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface

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12 December 2020

Association of genetic variants in the HDL receptor, SR-B1, with abnormal lipids in women with coronary artery disease

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12 December 2020

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

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12 December 2020

Regulation of platelet function by class B scavenger receptors in hyperlipidemia

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12 December 2020

Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe

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12 December 2020

Loading anticancer drugs into HDL as well as LDL has little affect on properties of complexes and enhances cytotoxicity to human carcinoma cells

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12 December 2020

Scavenger Receptor Class B Is Required for Hepatitis C Virus Uptake and Cross-Presentation by Human Dendritic Cells

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12 December 2020

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

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12 December 2020

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry

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12 December 2020

SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation.

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12 December 2020

Scavenger receptor BI (SR-BI) is up-regulated in adrenal gland in apolipoprotein A-I and hepatic lipase knock-out mice as a response to depletion of cholesterol stores. In vivo evidence that SR-BI is a functional high density lipoprotein receptor un

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12 December 2020

Sterol regulatory element-binding protein-1a binds to cis elements in the promoter of the rat high density lipoprotein receptor SR-BI gene.

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12 December 2020

Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors

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12 December 2020

Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI.

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12 December 2020

Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor.

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12 December 2020

Role for Rab7 in maturation of late autophagic vacuoles

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12 December 2020

Reconstituted lipoprotein: a versatile class of biologically-inspired nanostructures

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12 December 2020

SNARE-Mediated Cholesterol Movement to Mitochondria Supports Steroidogenesis in Rodent Cells

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12 December 2020

Stimulation of cholesterol efflux by LXR agonists in cholesterol-loaded human macrophages is ABCA1-dependent but ABCG1-independent

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12 December 2020

Signaling by the high-affinity HDL receptor scavenger receptor B type I.

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12 December 2020

Liver-specific overexpression of scavenger receptor BI decreases levels of very low density lipoprotein ApoB, low density lipoprotein ApoB, and high density lipoprotein in transgenic mice

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12 December 2020

SR-BI: Linking Cholesterol and Lipoprotein Metabolism with Breast and Prostate Cancer

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12 December 2020

Biological, clinical and population relevance of 95 loci for blood lipids

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12 December 2020

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

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12 December 2020

Cholesterol in signal transduction

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12 December 2020

Ribonucleic acid expression of the CLA-1 gene, a human homolog to mouse high density lipoprotein receptor SR-BI, in human adrenal tumors and cultured adrenal cells

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12 December 2020

Identification of the N-linked glycosylation sites on the high density lipoprotein (HDL) receptor SR-BI and assessment of their effects on HDL binding and selective lipid uptake

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12 December 2020

Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies

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12 December 2020

A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways

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12 December 2020

Differential roles of cysteine residues in the cellular trafficking, dimerization, and function of the high-density lipoprotein receptor, SR-BI.

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12 December 2020

Simultaneous induction of an HDL receptor protein (SR-BI) and the selective uptake of HDL-cholesteryl esters in a physiologically relevant steroidogenic cell model

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12 December 2020

Macrophage autophagy plays a protective role in advanced atherosclerosis

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12 December 2020

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome

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12 December 2020

Targeting the SR-B1 Receptor as a Gateway for Cancer Therapy and Imaging

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12 December 2020

MicroRNAs 185, 96, and 223 repress selective high-density lipoprotein cholesterol uptake through posttranscriptional inhibition

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12 December 2020

Regulation of the cholesterol ester cycle of cultured Leydig tumor cells

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12 December 2020

Structure and localization of the human gene encoding SR-BI/CLA-1. Evidence for transcriptional control by steroidogenic factor 1.

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12 December 2020

A nonendocytotic mechanism for the selective uptake of high density lipoprotein-associated cholesterol esters.

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12 December 2020

Scavenger receptor class B type I is a plasma membrane cholesterol sensor

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12 December 2020

Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo

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12 December 2020

Steroidogenic factor-1 mediates cyclic 3',5'-adenosine monophosphate regulation of the high density lipoprotein receptor

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12 December 2020

SR-BI: A Multifunctional Receptor in Cholesterol Homeostasis and Atherosclerosis

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12 December 2020

Intracellular events in the "selective" transport of lipoprotein-derived cholesteryl esters

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12 December 2020

SR-BI in bone marrow derived cells protects mice from diet induced coronary artery atherosclerosis and myocardial infarction

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12 December 2020

Impact of nanotechnology on drug delivery.

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12 December 2020

Lymphatic vessels are essential for the removal of cholesterol from peripheral tissues by SR-BI-mediated transport of HDL.

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12 December 2020

Developmental and hormonal regulation of murine scavenger receptor, class B, type 1.

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12 December 2020

Feedback inhibition of human scavenger receptor class B type I gene expression by glucocorticoid in adrenal and ovarian cells.

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12 December 2020

Scavenger receptor class B type I (SR-BI) is involved in vitamin E transport across the enterocyte

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12 December 2020

Scavenger receptor class B type I (SR-BI): a versatile receptor with multiple functions and actions

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12 December 2020

Scavenger receptor class B type I localizes to a late endosomal compartment

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12 December 2020

The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity.

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12 December 2020

High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion

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12 December 2020

Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure

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12 December 2020

Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels

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12 December 2020

Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase

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12 December 2020

CD36 homolog divergence is responsible for the selectivity of carotenoid species migration to the silk gland of the silkworm Bombyx mori

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12 December 2020

Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes

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12 December 2020

SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells

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12 December 2020

Human macrophage cholesterol efflux potential is enhanced by HDL-associated 17beta-estradiol fatty acyl esters.

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12 December 2020

Yin yang 1 protein negatively regulates high-density lipoprotein receptor gene transcription by disrupting binding of sterol regulatory element binding protein to the sterol regulatory element

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12 December 2020

Mechanism of scavenger receptor class B type I-mediated selective uptake of cholesteryl esters from high density lipoprotein to adrenal cells

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12 December 2020

Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins.

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12 December 2020

SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a).

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12 December 2020

Expression and microvillar localization of scavenger receptor class B, type I (SR-BI) and selective cholesteryl ester uptake in Leydig cells from rat testis

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12 December 2020

Scavenger receptor class B, type I-mediated uptake of various lipids into cells. Influence of the nature of the donor particle interaction with the receptor

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12 December 2020

Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36

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12 December 2020

Lipoprotein profiles in human heterozygote carriers of a functional mutation P297S in scavenger receptor class B1.

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12 December 2020

Genetic variant of the scavenger receptor BI in humans

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12 December 2020

Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport

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12 December 2020

SR-BI is required for microvillar channel formation and the localization of HDL particles to the surface of adrenocortical cells in vivo.

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12 December 2020

How hepatitis C virus invades hepatocytes: the mystery of viral entry

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12 December 2020

Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS) uptake and LPS-induced pro-inflammatory cytokine responses in THP-1 monocyte cells

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12 December 2020

A receptor-mediated pathway for cholesterol homeostasis

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12 December 2020

Current concept of reverse cholesterol transport and novel strategy for atheroprotection

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12 December 2020

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12 December 2020

Activation of the rat scavenger receptor class B type I gene by PPARalpha.

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12 December 2020

Expression of scavenger receptor class B type 1 (SR-BI) promotes microvillar channel formation and selective cholesteryl ester transport in a heterologous reconstituted system

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12 December 2020

Effects of hepatic expression of the high-density lipoprotein receptor SR-BI on lipoprotein metabolism and female fertility

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12 December 2020

Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol

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12 December 2020

Expression of SR-BI (Scavenger Receptor Class B Type I) in turtle (Chrysemys picta) tissues and other nonmammalian vertebrates

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12 December 2020

High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI

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12 December 2020

An ApoA-I mimetic peptide high-density-lipoprotein-based MRI contrast agent for atherosclerotic plaque composition detection

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12 December 2020

Atherogenic lipoprotein particles in atherosclerosis

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12 December 2020

Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I.

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12 December 2020

Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster.

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12 December 2020

Molecular mechanisms of cellular cholesterol efflux

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12 December 2020

The SNMP/CD36 gene family in Diptera, Hymenoptera and Coleoptera: Drosophila melanogaster, D. pseudoobscura, Anopheles gambiae, Aedes aegypti, Apis mellifera, and Tribolium castaneum

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12 December 2020

Comparison of expression and regulation of the high-density lipoprotein receptor SR-BI and the low-density lipoprotein receptor in human adrenocortical carcinoma NCI-H295 cells

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12 December 2020

10.1146/ANNUREV-PHYSIOL-021317-121550

Identifiers

DOI

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1 July 2019

PMC publication ID

6376870

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1 July 2019

PubMed publication ID

29125794

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1 July 2019