(Q46226618)

20 December 2017

title

Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation (English)

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20 December 2017

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11

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Rafick-Pierre Sékaly

20

object named as

Rafick Sekaly

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Amit Bar-or

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object named as

Amit Bar-Or

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Alexandre Prat

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object named as

Alexandre Prat

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20 December 2017

author name string

Peter J Darlington

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Tarik Touil

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Jean-Sebastien Doucet

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Denis Gaucher

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Joumana Zeidan

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Dominique Gauchat

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Rachel Corsini

7

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Ho Jin Kim

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Martin Duddy

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Farzaneh Jalili

10

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Hania Kebir

12

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Jacqueline Chen

13

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Douglas L Arnold

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Marjorie Bowman

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Jack Antel

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Mark S Freedman

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Harold Atkins

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Remi Cheynier

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Canadian MS/BMT Study Group

23

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publication date

5 March 2013

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20 December 2017

published in

Annals of Neurology

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20 December 2017

volume

73

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20 December 2017

issue

3

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20 December 2017

page(s)

341-354

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20 December 2017

Hematopoietic stem cell transplantation for multiple sclerosis. A retrospective multicenter study.

cites work

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High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis

21 January 2018

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High-dose immunosuppression with autologous stem cell transplantation in severe refractory systemic lupus erythematosus.

21 January 2018

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Myeloablative immunosuppressive treatment with autologous haematopoietic stem cell transplantation in a patient with psoriatic arthropathy and monoclonal gammopathy of undetermined significance

21 January 2018

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Suppressing immunity in advancing MS: too much too late, or too late for much?

21 January 2018

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The potential use of stem cells in multiple sclerosis: an overview of the preclinical experience

21 January 2018

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Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

21 January 2018

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Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis

21 January 2018

1 reference

Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients.

21 January 2018

1 reference

Immunological questions on hematopoietic stem cell transplantation for multiple sclerosis.

21 January 2018

1 reference

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

21 January 2018

1 reference

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

21 January 2018

1 reference

T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire

21 January 2018

1 reference

Tracing functional antigen-specific CCR6 Th17 cells after vaccination

21 January 2018

1 reference

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

21 January 2018

1 reference

Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis.

21 January 2018

1 reference

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Encephalitogenic T cells that stably express both T-bet and ROR gamma t consistently produce IFNgamma but have a spectrum of IL-17 profiles

21 January 2018

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T cells in multiple sclerosis and experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Immune ablation followed by autologous hematopoietic stem cell transplantation for the treatment of poor prognosis multiple sclerosis

21 January 2018

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Evidence for adequate thymic function but impaired naive T-cell survival following allogeneic hematopoietic stem cell transplantation in the absence of chronic graft-versus-host disease

21 January 2018

1 reference

Estimating thymic function through quantification of T-cell receptor excision circles

21 January 2018

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Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.

21 January 2018

1 reference

Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection

21 January 2018

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T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation

21 January 2018

1 reference

Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets

21 January 2018

1 reference

Quantification of T cell receptor rearrangement excision circles to estimate thymic function: an important new tool for endocrine-immune physiology.

21 January 2018

1 reference

Longitudinal study of antimyelin T-cell reactivity in relapsing-remitting multiple sclerosis: association with clinical and MRI activity.

21 January 2018

1 reference

Reactivity pattern and cytokine profile of T cells primed by myelin peptides in multiple sclerosis and healthy individuals

21 January 2018

1 reference

Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study

21 January 2018

1 reference

Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS.

21 January 2018

1 reference

Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: report of toxicity and immunological monitoring

21 January 2018

1 reference

Conventional dendritic cells are the critical donor APC presenting alloantigen after experimental bone marrow transplantation

21 January 2018

1 reference

Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

21 January 2018

1 reference

Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease

21 January 2018

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C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

21 January 2018

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CD161(high)CD8+T cells bear pathogenetic potential in multiple sclerosis.

21 January 2018

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CCR6 regulates the migration of inflammatory and regulatory T cells

21 January 2018

1 reference

Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial

21 January 2018

1 reference

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

21 January 2018

1 reference

Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANA.23784

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20 December 2017

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20 December 2017