(Q46227006)

20 December 2017

title

Statin reverses smoke-induced pulmonary hypertension and prevents emphysema but not airway remodeling (English)

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20 December 2017

main subject

pulmonary hypertension

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1 reference

6

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20 December 2017

author name string

Joanne L Wright

1

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20 December 2017

Steven Zhou

2

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20 December 2017

Olena Preobrazhenska

3

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20 December 2017

Caroline Marshall

4

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20 December 2017

Don D Sin

5

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20 December 2017

Saeid Golbidi

7

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20 December 2017

Andrew M Churg

8

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20 December 2017

language of work or name

English

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publication date

13 August 2010

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20 December 2017

American Journal of Respiratory and Critical Care Medicine

published in

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20 December 2017

volume

183

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20 December 2017

page(s)

50-58

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20 December 2017

issue

1

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20 December 2017

Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

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Usefulness of C-reactive protein and interleukin-6 as predictors of outcomes in patients with chronic obstructive pulmonary disease receiving pravastatin

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs

21 January 2018

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Simvastatin attenuates experimental small airway remodelling in rats

21 January 2018

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Testing drugs in animal models of cigarette smoke-induced chronic obstructive pulmonary disease

21 January 2018

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Reactive oxygen species and airway inflammation

21 January 2018

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Short-term exposure to cigarette smoke induces endothelial dysfunction in small intrapulmonary arteries: analysis using guinea pig precision cut lung slices

21 January 2018

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Pulmonary hypertension in chronic obstructive pulmonary disease: current theories of pathogenesis and their implications for treatment

21 January 2018

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Cigarette smoke induces persisting increases of vasoactive mediators in pulmonary arteries

21 January 2018

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Vasoactive mediators and pulmonary hypertension after cigarette smoke exposure in the guinea pig.

21 January 2018

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Effects of cigarette smoke on endothelial function of pulmonary arteries in the guinea pig.

21 January 2018

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Effect of HMG-CoA reductase inhibitors on vascular cell apoptosis: beneficial or detrimental?

21 January 2018

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Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells

21 January 2018

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Effects of statins on vascular function of endothelin-1.

21 January 2018

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Statins and their role in vascular protection

21 January 2018

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Pulmonary hypertension in COPD: epidemiology, significance, and management: pulmonary vascular disease: the global perspective

21 January 2018

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Mobility and invasiveness of metastatic esophageal cancer are potentiated by shear stress in a ROCK- and Ras-dependent manner

21 January 2018

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Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.

21 January 2018

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Lung particle overload: implications for occupational exposures to particles

21 January 2018

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Vascular dysfunction in chronic obstructive pulmonary disease.

21 January 2018

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Determinants of systemic vascular function in patients with stable chronic obstructive pulmonary disease.

21 January 2018

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Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release

21 January 2018

1 reference

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Dysfunctional endothelial nitric oxide biosynthesis in healthy smokers with impaired endothelium-dependent vasodilatation

21 January 2018

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Animal models of COPD: Barriers, successes, and challenges

21 January 2018

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Potential therapeutic role for statins in respiratory disease

21 January 2018

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Statin effects beyond lipid lowering--are they clinically relevant?

21 January 2018

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Statins suppress MMP2 secretion via inactivation of RhoA/ROCK pathway in pulmonary vascular smooth muscles cells

21 January 2018

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Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells

21 January 2018

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Effect of atorvastatin on TH1 and TH2 cytokine secreting cells during T cell activation and differentiation

21 January 2018

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Mechanisms of cigarette smoke-induced COPD: insights from animal models

21 January 2018

1 reference

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Immunologic aspects of chronic obstructive pulmonary disease

21 January 2018

1 reference

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Induction of macrophage elastase (MMP-12) gene expression by statins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201003-0399OC

Expression of profibrotic mediators in small airways versus parenchyma after cigarette smoke exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201003-0399OC

Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers

21 January 2018

1 reference

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Animal models of chronic obstructive pulmonary disease

21 January 2018

1 reference

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Airway Remodeling in the Smoke Exposed Guinea Pig Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201003-0399OC

10.1164/RCCM.201003-0399OC

21 January 2018

Identifiers

DOI

1 reference

20 December 2017

PubMed ID

20709821

1 reference

20 December 2017