(Q46238586)

20 December 2017

title

Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway (English)

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20 December 2017

author name string

Wenjun Zhang

1

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20 December 2017

Kenji Watanabe

2

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20 December 2017

Clay C C Wang

3

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20 December 2017

Yi Tang

4

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20 December 2017

language of work or name

English

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publication date

12 July 2007

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20 December 2017

Journal of Biological Chemistry

published in

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20 December 2017

volume

282

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20 December 2017

issue

35

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20 December 2017

page(s)

25717-25725

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20 December 2017

Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus

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Modification of post-PKS tailoring steps through combinatorial biosynthesis

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BIOSYNTHESIS OF THE TETRACYCLINES. 8. CHARACTERIZATION OF 4-HYDROXY-6-METHYLPRETETRAMID.

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Biosynthesis of tetracyclines. XI. The methylanthrone analog of protetrone

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Biosynthesis of the tetracyclines. IX. 4-Aminodedimethylaminoanhydrodemethylchlortetracycline from a mutant of Streptomyces aureofaciens

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Genetics of Streptomyces rimosus, the oxytetracycline producer.

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Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase

21 January 2018

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DnrD cyclase involved in the biosynthesis of doxorubicin: purification and characterization of the recombinant enzyme

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Elucidation of anthracyclinone biosynthesis by stepwise cloning of genes for anthracyclines from three different Streptomyces spp

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Structural and functional analysis of tetracenomycin F2 cyclase from Streptomyces glaucescens. A type II polyketide cyclase.

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Biosynthetic Studies of Daunorubicin and Tetracenomycin C

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A gene cluster encoding resistomycin biosynthesis in Streptomyces resistomycificus; exploring polyketide cyclization beyond linear and angucyclic patterns

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Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids.

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Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster

21 January 2018

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Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length

21 January 2018

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Novel polyketide metabolites from Streptomyces rimosus mutant strain R1059.

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Heterologous biosynthesis of amidated polyketides with novel cyclization regioselectivity from oxytetracycline polyketide synthase.

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Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity

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Malonyl-coenzyme A:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis.

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Context-dependent behavior of the enterocin iterative polyketide synthase; a new model for ketoreduction

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Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.

21 January 2018

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Honeybees' Distance Perception Changes with Terrain of Flight Path

21 January 2018

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Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits

21 January 2018

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The hedamycin locus implicates a novel aromatic PKS priming mechanism.

21 January 2018

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Production of aromatic minimal polyketides by the daunorubicin polyketide synthase genes reveals the incompatibility of the heterologous DpsY and JadI cyclases

21 January 2018

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21 January 2018

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Reconstitution of the iterative type II polyketide synthase for tetracenomycin F2 biosynthesis.

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Tetracenomycin M, a Novel Genetically Engineered Tetracenomycin Resulting from a Combination of Mithramycin and Tetracenomycin Biosynthetic Genes

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9 March 2024

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Isolation and chemical structure of aklanonic acid, an early intermediate in the biosynthesis of anthracyclines.

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https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.38.1034

The Streptomyces peucetius dpsY anddnrX Genes Govern Early and Late Steps of Daunorubicin and Doxorubicin Biosynthesis

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12 April 2024

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Identifiers

DOI

10.1074/JBC.M703437200

1 reference

20 December 2017

PubMed ID

17631493

1 reference

20 December 2017