(Q46253336)

20 December 2017

title

Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy (English)

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20 December 2017

author

Paul L. Greenhaff

5

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20 December 2017

author name string

Joanne E Mallinson

1

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20 December 2017

Dumitru Constantin-Teodosiu

2

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20 December 2017

James Sidaway

3

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20 December 2017

F Russell Westwood

4

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20 December 2017

language of work or name

English

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publication date

10 November 2008

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20 December 2017

published in

Journal of Physiology

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20 December 2017

volume

587

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20 December 2017

issue

1

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20 December 2017

page(s)

219-230

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20 December 2017

Statin myopathy as a metabolic muscle disease

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29 September 2018

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Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone

29 September 2018

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29 September 2018

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The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

29 September 2018

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The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

29 September 2018

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Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

29 September 2018

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29 September 2018

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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

29 September 2018

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Molecular mechanisms modulating muscle mass

29 September 2018

1 reference

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Fibrates and statins rapidly and synergistically induce pyruvate dehydrogenase kinase 4 mRNA in the liver and muscles of mice

29 September 2018

1 reference

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Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation

29 September 2018

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29 September 2018

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Gemfibrozil greatly increases plasma concentrations of cerivastatin

29 September 2018

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Statin-associated myopathy with normal creatine kinase levels

29 September 2018

1 reference

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Impact of HMG CoA reductase inhibition on small GTPases in the heart

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Induction of protein catabolism and the ubiquitin-proteasome pathway by mild oxidative stress.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Identification of cathepsin L as a differentially expressed message associated with skeletal muscle wasting

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha.

29 September 2018

1 reference

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Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways

29 September 2018

1 reference

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Metallothioneins, oxidative stress and the cardiovascular system

29 September 2018

1 reference

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Extraction of nuclear proteins from striated muscle tissue.

29 September 2018

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Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

RhoA GTPase and serum response factor control selectively the expression of MyoD without affecting Myf5 in mouse myoblasts

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

29 September 2018

Cytokines and cachexia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Cloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in human

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Experimental lovastatin myopathy.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Diversity of the pyruvate dehydrogenase kinase gene family in humans

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

The mammalian pyruvate dehydrogenase complex: structure and regulation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Regulation of the mevalonate pathway

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Experimental simvastatin-induced myopathy in rabbits

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Creatine kinase in serum: 1. Determination of optimum reaction conditions

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670035

Muscle composition in relation to age and sex

29 September 2018

1 reference

12 December 2020

Activation of the ATP-ubiquitin-proteasome pathway in skeletal muscle of cachectic rats bearing a hepatoma

1 reference

12 December 2020

Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes

1 reference

12 December 2020

Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro

1 reference

12 December 2020

3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

1 reference

12 December 2020

Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin

1 reference

12 December 2020

Simvastatin reduces insulin-like growth factor-1 signaling in differentiating C2C12 mouse myoblast cells in an HMG-CoA reductase inhibition-independent manner

1 reference

12 December 2020

PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle

1 reference

12 December 2020

Forkhead transcription factor FOXO subfamily is essential for reactive oxygen species-induced apoptosis

1 reference

12 December 2020

Muscle fiber type composition of the rat hindlimb

1 reference

12 December 2020

10.1113/JPHYSIOL.2008.164699

Identifiers

DOI

1 reference

20 December 2017

PMC publication ID

2670035

0 references

1 reference

20 December 2017