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Molecular mechanisms modulating muscle mass
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Molecular mechanisms modulating muscle mass
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
author name string
David J Glass
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
publication date
1 August 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
published in
Trends in Molecular Medicine
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
volume
9
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
page(s)
344-350
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
issue
8
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
cites work
Protein turnover measured in vivo and in vitro in muscles undergoing compensatory growth and subsequent denervation atrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
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inferred from DOI database lookup
Insulin and IGF-I induce pronounced hypertrophy of skeletal myofibers in tissue culture
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
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Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of cachexia in mice by systemically administered myostatin.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of ubiquitin ligases required for skeletal muscle atrophy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular actions of the insulin-like growth factor binding proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted expression of IGF-1 transgene to skeletal muscle accelerates muscle and motor neuron regeneration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Raf-Akt Cross-talk
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and regulation of Raf by Akt (protein kinase B)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras is involved in nerve-activity-dependent regulation of muscle genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of translocation in the activation and function of protein kinase B
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/protein kinase B promotes organ growth in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myogenic Akt signaling regulates blood vessel recruitment during myofiber growth.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of activation of protein kinase B by insulin and IGF-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protein phosphatase 2A: the Trojan Horse of cellular signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protean PTEN: form and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The lipid phosphatase SHIP2 controls insulin sensitivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cellular growth by the Drosophila target of rapamycin dTOR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila S6 kinase: a regulator of cell size
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and activation of p70s6k by PDK1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of eIF-4E BP1 phosphorylation by mTOR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Patterns of gene expression in atrophying skeletal muscles: response to food deprivation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atrophy responses to muscle inactivity. II. Molecular markers of protein deficits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The RING finger domain: a recent example of a sequence-structure family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Does this have a familiar RING?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tripartite motif family identifies cell compartments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SCF ubiquitin ligase: an extended look
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double muscling in cattle due to mutations in the myostatin gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of myostatin in adult mice increases skeletal muscle mass and strength
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional improvement of dystrophic muscle by myostatin blockade.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signalling pathways that mediate skeletal muscle hypertrophy and atrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1471-4914(03)00138-2
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
PubMed ID
12928036
1 reference
stated in
Europe PubMed Central
PubMed ID
12928036
retrieved
7 August 2017
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