(Q46255928)

20 December 2017

title

Loss of heterozygosity, aberrant methylation, BRAF mutation and KRAS mutation in colorectal signet ring cell carcinoma (English)

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20 December 2017

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3

Thomas C Smyrk

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20 December 2017

Sanjay Kakar

1

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20 December 2017

Guoren Deng

2

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20 December 2017

Lisa Cun

4

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20 December 2017

Vaibhav Sahai

5

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20 December 2017

Young S Kim

6

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20 December 2017

language of work or name

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20 April 2012

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20 December 2017

published in

Modern Pathology

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20 December 2017

volume

25

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20 December 2017

issue

7

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20 December 2017

page(s)

1040-1047

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20 December 2017

https://scigraph.springernature.com/pub.10.1038/modpathol.2012.44

exact match

0 references

cites work

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A 10-year outcomes evaluation of mucinous and signet-ring cell carcinoma of the colon and rectum

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Role of the serrated pathway in colorectal cancer pathogenesis

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Signet ring cell carcinoma of the colorectum: correlations between microsatellite instability, clinicopathologic features and survival.

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Genetic profiling of colorectal cancer liver metastases by combined comparative genomic hybridization and G-banding analysis.

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CpG island methylator phenotypes in aging and cancer.

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Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype

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Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands

21 January 2018

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CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

21 January 2018

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The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening status

21 January 2018

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Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer

21 January 2018

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Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample

21 January 2018

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Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points

21 January 2018

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Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma

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KRAS mutation in colon cancer: a marker of resistance to EGFR-I therapy

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Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer.

21 January 2018

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Primary mucinous adenocarcinomas and signet-ring cell carcinomas of colon and rectum

21 January 2018

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7 January 2021

Signet-ring cell carcinoma of the colon and rectum: a matched control study

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Molecular characteristics of poorly differentiated adenocarcinoma and signet-ring-cell carcinoma of colorectum

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Ordinary colorectal adenocarcinoma vs. primary colorectal signet-ring cell carcinoma: study matched for age, gender, grade, and stage

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Prognostic significance of recurrent chromosomal aberrations detected by comparative genomic hybridization in sporadic colorectal cancer

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7 January 2021

Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon Cancers

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation

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https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

Immunohistochemical staining patterns of MUC1, MUC2, MUC4, and MUC5AC mucins in hyperplastic polyps, serrated adenomas, and traditional adenomas of the colorectum

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2012.44

7 January 2021

10.1038/MODPATHOL.2012.44

Identifiers

DOI

1 reference

20 December 2017

PubMed ID

22522845

1 reference

20 December 2017