(Q46262329)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

main subject

microglia

0 references

reactive oxygen species

1 reference

7

1 reference

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25 December 2019

Michael R. Duchen

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Michele Mazzanti

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Rosemary H Milton

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Rosella Abeti

2

1 reference

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25 December 2019

Stefania Averaimo

3

1 reference

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25 December 2019

Silvia DeBiasi

4

1 reference

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25 December 2019

Laura Vitellaro

5

1 reference

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25 December 2019

Lele Jiang

6

1 reference

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25 December 2019

Samuel N Breit

8

1 reference

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25 December 2019

language of work or name

English

0 references

publication date

1 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

published in

Journal of Neuroscience

1 reference

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25 December 2019

volume

28

1 reference

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25 December 2019

issue

45

1 reference

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25 December 2019

page(s)

11488-11499

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease

25 December 2019

cites work

1 reference

12 December 2020

Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35].

1 reference

12 December 2020

Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells

1 reference

12 December 2020

Activation of NADPH oxidase in Alzheimer's disease brains.

1 reference

12 December 2020

Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species

1 reference

12 December 2020

Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column.

1 reference

12 December 2020

Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.

1 reference

12 December 2020

Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution

1 reference

12 December 2020

An energy budget for signaling in the grey matter of the brain

1 reference

12 December 2020

CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel

1 reference

12 December 2020

Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1

1 reference

12 December 2020

AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member

1 reference

12 December 2020

Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

1 reference

12 December 2020

The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels

1 reference

12 December 2020

Regulation of eosinophil membrane depolarization during NADPH oxidase activation

1 reference

12 December 2020

Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity.

1 reference

12 December 2020

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

12 December 2020

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

1 reference

12 December 2020

The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition

1 reference

12 December 2020

Interactions between NADPH oxidase and voltage-gated proton channels: why electron transport depends on proton transport.

1 reference

12 December 2020

The large-conductance Ca2+-activated K+ channel is essential for innate immunity

1 reference

12 December 2020

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

1 reference

12 December 2020

CLIC-5A functions as a chloride channel in vitro and associates with the cortical actin cytoskeleton in vitro and in vivo

1 reference

12 December 2020

Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity

1 reference

12 December 2020

A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells

1 reference

12 December 2020

Amyloid beta-peptide(1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain

1 reference

12 December 2020

Surface behavior and lipid interaction of Alzheimer beta-amyloid peptide 1-42: a membrane-disrupting peptide

1 reference

12 December 2020

NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide.

1 reference

12 December 2020

An immortalized cell line expresses properties of activated microglial cells

1 reference

12 December 2020

Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress.

1 reference

12 December 2020

Expression and modulation of an NADPH oxidase in mammalian astrocytes.

1 reference

12 December 2020

A key role for the microglial NADPH oxidase in APP-dependent killing of neurons

1 reference

12 December 2020

Consequences of the electrogenic function of the phagocytic NADPH oxidase

1 reference

12 December 2020

The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides

1 reference

12 December 2020

Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore

1 reference

12 December 2020

Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin.

1 reference

12 December 2020

Fibrillar beta-amyloid peptide Abeta1-40 activates microglial proliferation via stimulating TNF-alpha release and H2O2 derived from NADPH oxidase: a cell culture study

1 reference

12 December 2020

Inflammatory changes parallel the early stages of Alzheimer disease

1 reference

12 December 2020

The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease

1 reference

12 December 2020

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

1 reference

12 December 2020

Redox proteomics identification of oxidatively modified brain proteins in inherited Alzheimer's disease: an initial assessment

1 reference

12 December 2020

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.

1 reference

12 December 2020

Small-conductance Cl- channels contribute to volume regulation and phagocytosis in microglia.

1 reference

12 December 2020

Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

1 reference

12 December 2020

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

1 reference

12 December 2020

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

1 reference

12 December 2020

Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

1 reference

12 December 2020

The superoxide-generating NADPH oxidase of human neutrophils is electrogenic and associated with an H+ channel

1 reference

12 December 2020

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

1 reference

12 December 2020

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

1 reference

12 December 2020

An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease.

1 reference

12 December 2020

Molecular cloning and expression of a chloride ion channel of cell nuclei

1 reference

12 December 2020

Measurement and characterization of superoxide generation in microglial cells: evidence for an NADPH oxidase-dependent pathway

1 reference

12 December 2020

Involvement of stretch-activated Cl- channels in ramification of murine microglia.

1 reference

12 December 2020

10.1523/JNEUROSCI.2431-08.2008

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18987185%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

18987185

1 reference