(Q46310564)

21 December 2017

http://europepmc.org/abstract/MED/28882997

title

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease (English)

1 reference

21 December 2017

http://europepmc.org/abstract/MED/28882997

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Joseph R Mazzulli

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Enrico Zampese

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Yvette C Wong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

David P Santos

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Judith Blanz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Carolin D Obermaier

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Chelsee Strojny

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Evangelos Kiskinis

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Xiaoxi Zhuang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Rejko Krüger

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Dimitri Krainc

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Pingping Song

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Sohee Jeon

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jeffrey N Savas

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

D James Surmeier

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

English

0 references

publication date

7 September 2017

1 reference

21 December 2017

http://europepmc.org/abstract/MED/28882997

published in

Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

6357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

1255-1261

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies

12 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Selective neuronal vulnerability in Parkinson disease

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Proteomic characterization of neuromelanin granules isolated from human substantia nigra by laser-microdissection.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

DJ-1 linked parkinsonism (PARK7) is associated with Lewy body pathology.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Detection of Free and Protein-Bound ortho-Quinones by Near-Infrared Fluorescence

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Mitochondrial dysfunction associated with glucocerebrosidase deficiency

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Calcineurin determines toxic versus beneficial responses to α-synuclein

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Human iPSC-based modeling of late-onset disease via progerin-induced aging

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Phase II safety, tolerability, and dose selection study of isradipine as a potential disease-modifying intervention in early Parkinson's disease (STEADY-PD).

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Genetic animal models of Parkinson's disease

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Robust pacemaking in substantia nigra dopaminergic neurons

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6021018

29 September 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Methods to monitor chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAM9080

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAM9080

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28882997%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference