(Q46311037)

21 December 2017

title

Neuromelanin in Parkinson's Disease: from Fenton Reaction to Calcium Signaling (English)

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21 December 2017

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28879408%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Rainer Knörle

series ordinal

1

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21 December 2017

publication date

6 September 2017

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21 December 2017

published in

Neurotoxicity Research

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28879408%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28879408%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28879408%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

515-522

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28879408%20AND%20SRC:MED&resulttype=core&format=json

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

12 June 2020

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease

21 January 2018

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21 January 2018

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Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Modifications of the iron-neuromelanin system in Parkinson's disease

21 January 2018

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Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease

21 January 2018

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Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis

21 January 2018

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Synthesis, Structure Characterization, and Evaluation in Microglia Cultures of Neuromelanin Analogues Suitable for Modeling Parkinson's Disease.

21 January 2018

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Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease

21 January 2018

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Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease

21 January 2018

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21 January 2018

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Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.

21 January 2018

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Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

21 January 2018

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Melanin has a role in Ca2+ homeostasis in human melanocytes.

21 January 2018

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Melanin protects melanocytes and keratinocytes against H2O2-induced DNA strand breaks through its ability to bind Ca2+.

21 January 2018

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Parkinson's disease is associated with altered expression of CaV1 channels and calcium-binding proteins.

21 January 2018

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Does tyrosinase exist in neuromelanin-pigmented neurons in the human substantia nigra?

21 January 2018

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The melanin binding of drugs and its implications

21 January 2018

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Iron-melanin complex in substantia nigra of parkinsonian brains: an x-ray microanalysis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A critical review of the function of neuromelanin and an attempt to provide a unified theory

21 January 2018

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Neuromelanin is an immune stimulator for dendritic cells in vitro

21 January 2018

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A possible role for humoral immunity in the pathogenesis of Parkinson's disease

21 January 2018

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The role of alpha-synuclein in melanin synthesis in melanoma and dopaminergic neuronal cells

21 January 2018

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21 January 2018

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Magnetic resonance correlation of iron content with neuromelanin in the substantia nigra of early-stage Parkinson's disease.

21 January 2018

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21 January 2018

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21 January 2018

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Protective and toxic roles of dopamine in Parkinson's disease

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Calcium, ageing, and neuronal vulnerability in Parkinson's disease

21 January 2018

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The origins of oxidant stress in Parkinson's disease and therapeutic strategies.

21 January 2018

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21 January 2018

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The structure of neuromelanin as studied by chemical degradative methods

21 January 2018

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Interaction between Neuromelanin and Alpha-Synuclein in Parkinson's Disease

21 January 2018

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Tyrosinase mRNA is expressed in human substantia nigra

21 January 2018

1 reference

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Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-017-9804-Z

The role of Ca2+ signaling in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-017-9804-Z

The effect of a synthetic neuromelanin on yield of free hydroxyl radicals generated in model systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-017-9804-Z

Neuromelanin can protect against iron-mediated oxidative damage in system modeling iron overload of brain aging and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-017-9804-Z

Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-017-9804-Z

Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-017-9804-Z

Calcium dysregulation and homeostasis of neural calcium in the molecular mechanisms of neurodegenerative diseases provide multiple targets for neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-017-9804-Z

Possible role of neuromelanin in the pathogenesis of Parkinson's disease

21 January 2018

1 reference

12 December 2020

Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain

1 reference

12 December 2020

Catecholamines oxidation by xanthine oxidase

1 reference

12 December 2020

Free radical scavenging properties of melanin interaction of eu- and pheo-melanin models with reducing and oxidising radicals

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12 December 2020

Arguments against the significance of the Fenton reaction contributing to signal pathways under in vivo conditions

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12 December 2020

Substantia nigra neuromelanin: structure, synthesis, and molecular behaviour

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12 December 2020

The relevance of iron in the pathogenesis of Parkinson's disease

1 reference

12 December 2020

Selective vulnerability of pigmented dopaminergic neurons in Parkinson's disease

1 reference

12 December 2020

Tyrosinase is not detected in human catecholaminergic neurons by immunohistochemistry and Western blot analysis

1 reference

12 December 2020

Interaction of radicals from water radiolysis with melanin

1 reference

12 December 2020

Pigment granules: a calcium reservoir in the vertebrate eye

1 reference

12 December 2020

Interaction of melanin with carbon- and oxygen-centered radicals from methanol and ethanol

1 reference

12 December 2020

Melanin concentration in normal human retinal pigment epithelium. Regional variation and age-related reduction.

1 reference

12 December 2020

Lipoxygenase-Catalyzed Oxidation of Catecholamines

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12 December 2020

The absolute concentration of nigral neuromelanin, assayed by a new sensitive method, increases throughout the life and is dramatically decreased in Parkinson's disease

1 reference

12 December 2020

Role of melanin as a scavenger of active oxygen species

1 reference

12 December 2020

Iron and other metals in neuromelanin, substantia nigra, and putamen of human brain

1 reference

12 December 2020

1 reference

12 December 2020

Pigmentation in the nucleus substantiae nigrae of mammals.

1 reference

12 December 2020

Quantification of Ca(2+) binding to melanin supports the hypothesis that melanosomes serve a functional role in regulating calcium homeostasis

1 reference

12 December 2020

Epidemiology of Parkinson's disease—An overview

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12 December 2020

Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease.

1 reference

12 December 2020

Antioxidant action of neuromelanin: the mechanism of inhibitory effect on lipid peroxidation

1 reference

12 December 2020

The effect of melanin on iron associated decomposition of hydrogen peroxide

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12 December 2020

Calcium uptake, release and ryanodine binding in melanosomes from retinal pigment epithelium

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12 December 2020

Possible involvement of complement factor C1q in the clearance of extracellular neuromelanin from the substantia nigra in Parkinson disease

1 reference

12 December 2020

1 reference

12 December 2020

10.1007/S12640-017-9804-Z

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28879408%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference