(Q36404133)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

Expanding insights of mitochondrial dysfunction in Parkinson's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Nicholas W. Wood

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Patrick M Abou-Sleiman

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

1 March 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Neuroscience

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

207-219

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16495942%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrn1868

17 January 2020

exact match

0 references

cites work

Alpha-synuclein in Lewy bodies

1 reference

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

21 January 2018

1 reference

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

21 January 2018

1 reference

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

21 January 2018

1 reference

Mitochondrial involvement in Parkinson's disease

21 January 2018

1 reference

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

1 reference

Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study.

21 January 2018

1 reference

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 January 2018

1 reference

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

21 January 2018

1 reference

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

1 reference

The ubiquitin pathway in Parkinson's disease.

21 January 2018

1 reference

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

21 January 2018

1 reference

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

21 January 2018

1 reference

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

1 reference

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

21 January 2018

1 reference

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

1 reference

Neurodegenerative disease: amyloid pores from pathogenic mutations.

21 January 2018

1 reference

Alpha-synuclein in blood and brain from familial Parkinson disease with SNCA locus triplication.

21 January 2018

1 reference

alpha-Synuclein is phosphorylated in synucleinopathy lesions

21 January 2018

1 reference

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

21 January 2018

1 reference

A Drosophila model of Parkinson's disease

21 January 2018

1 reference

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

21 January 2018

1 reference

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

21 January 2018

1 reference

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

21 January 2018

1 reference

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease

21 January 2018

1 reference

Parkin suppresses wild-type alpha-synuclein-induced toxicity in SHSY-5Y cells

21 January 2018

1 reference

Alpha-synuclein and neurodegenerative diseases

21 January 2018

1 reference

Models of Parkinson's disease

21 January 2018

1 reference

Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity

21 January 2018

1 reference

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

21 January 2018

1 reference

Mice lacking alpha-synuclein are resistant to mitochondrial toxins

21 January 2018

1 reference

Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

21 January 2018

1 reference

A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease

21 January 2018

1 reference

Association between early-onset Parkinson's disease and mutations in the parkin gene

21 January 2018

1 reference

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

1 reference

Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain

21 January 2018

1 reference

The ubiquitin-proteasome pathway: on protein death and cell life

21 January 2018

1 reference

Lewy bodies and parkinsonism in families with parkin mutations

21 January 2018

1 reference

Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations.

21 January 2018

1 reference

Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients

21 January 2018

1 reference

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

21 January 2018

1 reference

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

21 January 2018

1 reference

Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis.

21 January 2018

1 reference

Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

21 January 2018

1 reference

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

21 January 2018

1 reference

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

21 January 2018

1 reference

Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

21 January 2018

1 reference

Parkin-deficient mice are not a robust model of parkinsonism

21 January 2018

1 reference

Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study

21 January 2018

1 reference

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

21 January 2018

1 reference

Peripheral benzodiazepine receptors and mitochondrial function

21 January 2018

1 reference

Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2

21 January 2018

1 reference

Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults

21 January 2018

1 reference

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

21 January 2018

1 reference

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

21 January 2018

1 reference

Dopamine covalently modifies and functionally inactivates parkin

21 January 2018

1 reference

Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function.

21 January 2018

1 reference

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration

21 January 2018

1 reference

Ubiquitin-protein ligases

21 January 2018

1 reference

Parkin-associated Parkinson's disease

21 January 2018

1 reference

Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1

21 January 2018

1 reference

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

21 January 2018

1 reference

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

21 January 2018

1 reference

SEPT5_v2 is a parkin-binding protein

21 January 2018

1 reference

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

21 January 2018

1 reference

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

1 reference

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

21 January 2018

1 reference

The role of pathogenic DJ-1 mutations in Parkinson's disease.

21 January 2018

1 reference

DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia.

21 January 2018

1 reference

The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease

21 January 2018

1 reference

Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death

21 January 2018

1 reference

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

21 January 2018

1 reference

The biochemistry of Parkinson's disease

21 January 2018

1 reference

DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

21 January 2018

1 reference

DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin

21 January 2018

1 reference

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

21 January 2018

1 reference

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

21 January 2018

1 reference

Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

21 January 2018

1 reference

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

21 January 2018

1 reference

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

21 January 2018

1 reference

DJ-1, a novel regulator of the tumor suppressor PTEN.

21 January 2018

1 reference

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

21 January 2018

1 reference

The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease

21 January 2018

1 reference

Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease

21 January 2018

1 reference

The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

21 January 2018

1 reference

L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system

21 January 2018

1 reference

The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes

21 January 2018

1 reference

DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

21 January 2018

1 reference

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.

21 January 2018

1 reference

BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential

21 January 2018

1 reference

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.

21 January 2018

1 reference

Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease

21 January 2018

1 reference

Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes.

21 January 2018

1 reference

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

21 January 2018

1 reference

Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism

21 January 2018

1 reference

How mitochondria import hydrophilic and hydrophobic proteins.

21 January 2018

1 reference

Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations

21 January 2018

1 reference

Analysis of steady-state protein phosphorylation in mitochondria using a novel fluorescent phosphosensor dye.

21 January 2018

1 reference

The phosphorylation of subunits of complex I from bovine heart mitochondria.

21 January 2018

1 reference

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

21 January 2018

1 reference

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

21 January 2018

1 reference

Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi

21 January 2018

1 reference

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

21 January 2018

1 reference

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

21 January 2018

1 reference

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

21 January 2018

1 reference

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

21 January 2018

1 reference

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

21 January 2018

1 reference

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

21 January 2018

1 reference

Apoptosis in Parkinson's disease: signals for neuronal degradation

21 January 2018

1 reference

Targeting programmed cell death in neurodegenerative diseases

21 January 2018

1 reference

Bioenergetic and oxidative stress in neurodegenerative diseases

21 January 2018

1 reference

21 January 2018

Genetics of longevity.

1 reference

Proteasome inhibition alters neural mitochondrial homeostasis and mitochondria turnover

21 January 2018

1 reference

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

21 January 2018

1 reference

An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells

21 January 2018

1 reference

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

21 January 2018

1 reference

Deadly encounter: ubiquitin meets apoptosis

21 January 2018

1 reference

21 January 2018

Surfing the p53 network

1 reference

Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress

21 January 2018

1 reference

Mitochondrial function and dysfunction in the cell: its relevance to aging and aging-related disease

21 January 2018

1 reference

Mitochondria in health and disease: perspectives on a new mitochondrial biology

21 January 2018

1 reference

alpha-synuclein gene haplotypes are associated with Parkinson's disease

21 January 2018

1 reference

Mitochondrial mechanisms of neural cell death and neuroprotective interventions in Parkinson's disease.

21 January 2018

1 reference

Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease

31 March 2020

1 reference

Abnormalities of the electron transport chain in idiopathic Parkinson's disease

31 March 2020

1 reference

Mitochondrial complex I deficiency in Parkinson's disease

31 March 2020

1 reference

A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.

31 March 2020

1 reference

Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

31 March 2020

1 reference

Limited-time exposure to mitochondrial toxins may lead to chronic progressive neurodegenerative diseases

31 March 2020

1 reference

Proteasome inhibitors induce cytochrome c-caspase-3-like protease-mediated apoptosis in cultured cortical neurons.

31 March 2020

1 reference

Parkin and endoplasmic reticulum stress

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

1 reference