(Q46330715)

21 December 2017

title

Ligand unbinding pathways from the vitamin D receptor studied by molecular dynamics simulations (English)

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21 December 2017

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Mikael Peräkylä

1

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21 December 2017

publication date

3 October 2008

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21 December 2017

European Biophysics Journal

published in

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21 December 2017

volume

38

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21 December 2017

issue

2

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21 December 2017

page(s)

185-198

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21 December 2017

describes a project that uses

molecular dynamics simulation

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https://scigraph.springernature.com/pub.10.1007/s00249-008-0369-x

inferred from title

exact match

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cites work

Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

1 reference

12 December 2020

A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations

1 reference

12 December 2020

Partial agonists activate PPARgamma using a helix 12 independent mechanism

1 reference

12 December 2020

A dynamic mechanism of nuclear receptor activation and its perturbation in a human disease.

1 reference

12 December 2020

Comparison of multiple Amber force fields and development of improved protein backbone parameters

1 reference

12 December 2020

Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

1 reference

12 December 2020

Ligand dissociation from estrogen receptor is mediated by receptor dimerization: evidence from molecular dynamics simulations

1 reference

12 December 2020

Development and testing of a general amber force field

1 reference

12 December 2020

Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4.

1 reference

12 December 2020

Nuclear receptor structure: implications for function

1 reference

12 December 2020

Allosteric control of ligand selectivity between estrogen receptors alpha and beta: implications for other nuclear receptors

1 reference

12 December 2020

Targeted molecular dynamics: a new approach for searching pathways of conformational transitions

1 reference

12 December 2020

Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator

1 reference

12 December 2020

Retinoic acid receptor: a simulation analysis of retinoic acid binding and the resulting conformational changes

1 reference

12 December 2020

Putative helices 3 and 5 of the human vitamin D3 receptor are important for the binding of calcitriol

1 reference

12 December 2020

Nuclear receptors and lipid physiology: opening the X-files

1 reference

12 December 2020

Nuclear receptor minireview series

1 reference

12 December 2020

Chromophore channeling in the G-protein coupled receptor rhodopsin

1 reference

12 December 2020

How do substrates enter and products exit the buried active site of cytochrome P450cam? 1. Random expulsion molecular dynamics investigation of ligand access channels and mechanisms.

1 reference

12 December 2020

A structural role for hormone in the thyroid hormone receptor.

1 reference

12 December 2020

Steered molecular dynamics and mechanical functions of proteins

1 reference

12 December 2020

Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome

1 reference

12 December 2020

Mechanism of the nuclear receptor molecular switch

1 reference

12 December 2020

Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling

1 reference

12 December 2020

Critical role of helix 12 of the vitamin D(3) receptor for the partial agonism of carboxylic ester antagonists

1 reference

12 December 2020

Possible pathway for ubiquinone shuttling in Rhodospirillum rubrum revealed by molecular dynamics simulation

1 reference

12 December 2020

Vitamin D receptor as an intestinal bile acid sensor

1 reference

12 December 2020

Ligand binding and nuclear receptor evolution

1 reference

12 December 2020

Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation

1 reference

12 December 2020

Unbinding of retinoic acid from the retinoic acid receptor by random expulsion molecular dynamics

1 reference

12 December 2020

Unbinding of retinoic acid from its receptor studied by steered molecular dynamics

1 reference

12 December 2020

Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin

1 reference

12 December 2020

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

1 reference

12 December 2020

VMD: visual molecular dynamics

1 reference

12 December 2020

Ligand-escape pathways from the ligand-binding domain of PPARgamma receptor as probed by molecular dynamics simulations

1 reference

12 December 2020

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

1 reference

12 December 2020

Ligand-induced changes in estrogen receptor conformation as measured by site-directed spin labeling

1 reference

12 December 2020

The free energy landscapes governing conformational changes in a glutamate receptor ligand-binding domain

1 reference

12 December 2020

The nuclear receptor ligand-binding domain: structure and function

1 reference

12 December 2020

Do mammalian cytochrome P450s show multiple ligand access pathways and ligand channelling?

1 reference

12 December 2020

The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities

1 reference

12 December 2020

Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain

1 reference

12 December 2020

Probing a Water Channel near the A-Ring of Receptor-Bound 1α,25-Dihydroxyvitamin D3 with Selected 2α-Substituted Analogues†

1 reference

12 December 2020

Molecular dynamics simulations reveal multiple pathways of ligand dissociation from thyroid hormone receptors

1 reference

12 December 2020

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

1 reference

12 December 2020

Activation of nuclear receptors: a perspective from structural genomics

1 reference

12 December 2020

Molecular dynamics simulations of ligand dissociation from thyroid hormone receptors: evidence of the likeliest escape pathway and its implications for the design of novel ligands

1 reference

12 December 2020

Vitamin D receptor: ligand recognition and allosteric network

1 reference

12 December 2020

Ligands differentially modulate the protein interactions of the human estrogen receptors alpha and beta

1 reference

12 December 2020

10.1007/S00249-008-0369-X

Identifiers

DOI

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21 December 2017

release_wx6vzg6suvcynei2occpmco4jq

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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21 December 2017