(Q46335647)

18 February 2018

title

Uncoupling protein 1 controls reactive oxygen species in brown adipose tissue (English)

1 reference

18 February 2018

main subject

reactive oxygen species

1 reference

1

Martin Jastroch

1 reference

18 February 2018

language of work or name

English

0 references

publication date

14 July 2017

1 reference

18 February 2018

Proceedings of the National Academy of Sciences of the United States of America

published in

1 reference

18 February 2018

volume

114

1 reference

18 February 2018

issue

30

1 reference

18 February 2018

page(s)

7744-7746

1 reference

18 February 2018

UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

The molecular features of uncoupling protein 1 support a conventional mitochondrial carrier-like mechanism

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Brown adipose tissue: physiological function and evolutionary significance

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Brite/beige fat and UCP1 - is it thermogenesis?

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Brown fat in a protoendothermic mammal fuels eutherian evolution

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

The regulation and physiology of mitochondrial proton leak

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Mitochondrial proton and electron leaks

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

The role of UCP 1 in production of reactive oxygen species by mitochondria isolated from brown adipose tissue

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Aging: a theory based on free radical and radiation chemistry

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Uncoupling to survive? The role of mitochondrial inefficiency in ageing

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

A novel regulatory mechanism for the brown-fat uncoupling protein?

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Absence of adaptive nonshivering thermogenesis in a marsupial, the fat-tailed dunnart (Sminthopsis crassicaudata).

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Uncoupling protein 1 decreases superoxide production in brown adipose tissue mitochondria

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Cold tolerance of UCP1-ablated mice: a skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544340

Measurement of proton leak and electron leak in isolated mitochondria

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28710335

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28710335

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28710335

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1709064114

1 reference

18 February 2018

PMC publication ID

5544340

1 reference

18 February 2018

PubMed publication ID

28710335

1 reference

18 February 2018