(Q46359470)

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Local application of statin promotes bone repair through the suppression of osteoclasts and the enhancement of osteoblasts at bone-healing sites in rats

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Local application of statin promotes bone repair through the suppression of osteoclasts and the enhancement of osteoblasts at bone-healing sites in rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

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author name string

Yasunori Ayukawa

1

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Eisuke Yasukawa

2

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Yasuko Moriyama

3

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Yoichiro Ogino

4

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Hiroko Wada

5

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Ikiru Atsuta

6

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Kiyoshi Koyano

7

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

publication date

17 September 2008

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

107

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

3

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

336-342

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

Regulation of the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Lovastatin inhibits tumor growth and metastasis development of a rat fibrosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

1 reference

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7 January 2021

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

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Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

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Statins as a newly recognized type of immunomodulator

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Stimulation of bone formation in vitro and in rodents by statins

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Statin given perorally to adult rats increases cancellous bone mass and compressive strength

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Simvastatin promotes osteogenesis around titanium implants

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Statin use, clinical fracture, and bone density in postmenopausal women: results from the Women's Health Initiative Observational Study

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

The effect of fluvastatin on parameters of bone remodeling

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Does simvastatin stimulate bone formation in vivo?

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Statin collagen grafts used to repair defects in the parietal bone of rabbits.

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Locally applied simvastatin promotes fracture healing in ovariectomized rat

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Effect of local simvastatin application on mandibular defects.

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Expression profiles of mRNAs for osteoblast and osteoclast proteins as indicators of bone loss in mouse immobilization osteopenia model.

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NF kappa B ligand (RANKL) or tumor necrosis factor-alpha (TNF-alpha).

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Statin stimulates bone morphogenetic protein-2, aggrecan, and type 2 collagen gene expression and proteoglycan synthesis in rat chondrocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Osteoclast deficiency results in disorganized matrix, reduced mineralization, and abnormal osteoblast behavior in developing bone

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Bisphosphonate (YM529) delays the repair of cortical bone defect after drill-hole injury by reducing terminal differentiation of osteoblasts in the mouse femur

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Compactin suppresses bone resorption by inhibiting the fusion of prefusion osteoclasts and disrupting the actin ring in osteoclasts.

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femur

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Atorvastatin stimulates the production of osteoprotegerin by human osteoblasts.

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRIPLEO.2008.07.013

7 January 2021

Identifiers

10.1016/J.TRIPLEO.2008.07.013

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18801677

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