(Q46405400)

21 December 2017

title

Defective PTEN regulation contributes to B cell hyperresponsiveness in systemic lupus erythematosus (English)

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21 December 2017

author name string

Xiang-ni Wu

1

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21 December 2017

Yan-xia Ye

2

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21 December 2017

Jing-wen Niu

3

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21 December 2017

Yang Li

4

1 reference

21 December 2017

Xin Li

5

1 reference

21 December 2017

Xin You

6

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21 December 2017

Hua Chen

7

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21 December 2017

Li-dan Zhao

8

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21 December 2017

Xiao-feng Zeng

9

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21 December 2017

Feng-chun Zhang

10

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21 December 2017

Fu-lin Tang

11

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21 December 2017

Wei He

12

1 reference

21 December 2017

Xue-tao Cao

13

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21 December 2017

Xuan Zhang

14

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21 December 2017

Peter E Lipsky

15

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21 December 2017

language of work or name

English

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publication date

1 July 2014

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21 December 2017

Science Translational Medicine

published in

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21 December 2017

volume

6

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21 December 2017

issue

246

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21 December 2017

page(s)

246ra99

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21 December 2017

Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

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21 January 2018

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identification of cellular intermediates and molecular pathways induced by IL-21 in human B cells

21 January 2018

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B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

21 January 2018

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Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis

21 January 2018

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Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis

21 January 2018

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IL-21 administration into the nostril alleviates murine allergic rhinitis

21 January 2018

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21 January 2018

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MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

21 January 2018

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miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics

21 January 2018

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MicroRNA-22 promotes cell survival upon UV radiation by repressing PTEN.

21 January 2018

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21 January 2018

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21 January 2018

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Distinct response in maintenance of human naive and memory B cells via IL-21 receptor and TCL1/Akt pathways.

21 January 2018

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21 January 2018

New insights into PTEN.

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009131

BCR-mediated apoptosis associated with negative selection of immature B cells is selectively dependent on Pten.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009131

Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis

21 January 2018

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IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

21 January 2018

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21 January 2018

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MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma

21 January 2018

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EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF.

21 January 2018

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Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009131

Calcium signalling and cell-fate choice in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009131

Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3009131

10.1126/SCITRANSLMED.3009131

21 January 2018

Identifiers

DOI

1 reference

21 December 2017

1 reference

21 December 2017