(Q46410384)

22 December 2017

title

Tuberculosis vaccines: current progress (English)

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22 December 2017

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1

Ian M Orme

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22 December 2017

publication date

1 January 2005

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22 December 2017

published in

Drugs

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22 December 2017

volume

65

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22 December 2017

issue

17

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22 December 2017

page(s)

2437-2444

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22 December 2017

https://scigraph.springernature.com/pub.10.2165/00003495-200565170-00002

exact match

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The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

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A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis.

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NK cells respond to pulmonary infection with Mycobacterium tuberculosis, but play a minimal role in protection.

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12 December 2020

10.2165/00003495-200565170-00002

Identifiers

DOI

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22 December 2017

Dimensions Publication ID

1008321740

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22 December 2017