(Q46416832)

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Beta cell glucose sensitivity is decreased by 39% in non-diabetic individuals carrying multiple diabetes-risk alleles compared with those with no risk alleles.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Beta cell glucose sensitivity is decreased by 39% in non-diabetic individuals carrying multiple diabetes-risk alleles compared with those with no risk alleles (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Michael N Weedon

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Eleuterio Ferrannini

6

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E Ferrannini

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

L Pascoe

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

A Mari

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

A Tura

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

M Walker

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

RISC Consortium

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

publication date

22 August 2008

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

51

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1989-1992

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719881%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing insulin secretion by modeling in multiple-meal tests: role of potentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comment on: Gale EAM (2005) Spring harvest? Reflections on the rise of type 1 diabetes. Diabetologia 48:2245-2250; and Walker M, Mari A, Jayapaul MK et al (2005) Impaired beta cell glucose sensitivity and whole-body insulin sensitivity as predictors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18719881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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