(Q46438642)

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Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.

scientific article published on 14 April 2005

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831495%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831495%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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Aleksandra Filipovska

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831495%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Michael P. Murphy

6

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10 January 2020

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Geoffrey F Kelso

2

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10 January 2020

Stephanie E Brown

3

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10 January 2020

Samantha M Beer

4

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10 January 2020

Robin A J Smith

5

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10 January 2020

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14 April 2005

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10 January 2020

Journal of Biological Chemistry

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10 January 2020

280

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10 January 2020

25

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10 January 2020

24113-24126

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10 January 2020

Mitochondrial diseases in man and mouse

1 reference

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21 January 2018

The genetics and pathology of oxidative phosphorylation

1 reference

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21 January 2018

Mitochondria, oxygen free radicals, disease and ageing

1 reference

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21 January 2018

Oxidants, oxidative stress and the biology of ageing

1 reference

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21 January 2018

Oxygen radicals and signaling

1 reference

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21 January 2018

Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells.

1 reference

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21 January 2018

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

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21 January 2018

Molecular actions of Ebselen—an antiinflammatory antioxidant

1 reference

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21 January 2018

Chemistry of biologically important synthetic organoselenium compounds.

1 reference

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21 January 2018

Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis

1 reference

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21 January 2018

Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage.

1 reference

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21 January 2018

Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

1 reference

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21 January 2018

Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia

1 reference

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21 January 2018

Ebselen: prospective therapy for cerebral ischaemia

1 reference

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21 January 2018

Kinetic study of the reaction of ebselen with peroxynitrite.

1 reference

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21 January 2018

Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501148200

21 January 2018

Sulfur and selenium: the role of oxidation state in protein structure and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501148200

21 January 2018

A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase

1 reference

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21 January 2018

Oxidative damage to mitochondria and protection by ebselen and other antioxidants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501148200

21 January 2018

Dual effect of ebselen on mitochondrial permeability transition

1 reference

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21 January 2018

Selective targeting of bioactive compounds to mitochondria

1 reference

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21 January 2018

Development of lipophilic cations as therapies for disorders due to mitochondrial dysfunction

1 reference

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21 January 2018

Delivery of bioactive molecules to mitochondria in vivo.

1 reference

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21 January 2018

Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties

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21 January 2018

Selective targeting of an antioxidant to mitochondria

1 reference

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21 January 2018

Drug delivery to mitochondria: the key to mitochondrial medicine

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21 January 2018

Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants.

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21 January 2018

Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells

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21 January 2018

Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival

1 reference

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21 January 2018

Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501148200

21 January 2018

Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501148200

21 January 2018

Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis

1 reference

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21 January 2018

Specific modification of mitochondrial protein thiols in response to oxidative stress: a proteomics approach

1 reference

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21 January 2018

Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE.

1 reference

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21 January 2018

Measurement of protein using bicinchoninic acid

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21 January 2018

Thermodynamic control of electron flux through mitochondrial cytochrome bc1 complex

1 reference

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21 January 2018

Energy transduction in intact synaptosomes. Influence of plasma-membrane depolarization on the respiration and membrane potential of internal mitochondria determined in situ

1 reference

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21 January 2018

Uptake and accumulation of 1-methyl-4-phenylpyridinium by rat liver mitochondria measured using an ion-selective electrode

1 reference

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21 January 2018

Specific targeting of a DNA-alkylating reagent to mitochondria. Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide

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21 January 2018

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21 January 2018

Interaction of ebselen with glutathione S-transferase and papain in vitro

1 reference

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21 January 2018

Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology.

1 reference

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21 January 2018

Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway

1 reference

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21 January 2018

A novel biologically active seleno-organic compound—1

1 reference

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21 January 2018

Mechanism of Coupling of Oxidative Phosphorylation and the Membrane Potential of Mitochondria

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21 January 2018

Identifiers

10.1074/JBC.M501148200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831495%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15831495%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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