(Q46443857)

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Activation of G proteins and extracellular signal-regulated kinase 1/2 phosphorylation via human dopamine D4.4 receptors: differential pathway-dependent potencies of receptor agonists

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Activation of G proteins and extracellular signal-regulated kinase 1/2 phosphorylation via human dopamine D4.4 receptors: differential pathway-dependent potencies of receptor agonists (English)

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

phosphorylation

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author name string

Peter Heusler

1

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Liesbeth Bruins Slot

2

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Isabelle Rauly-Lestienne

3

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Christiane Palmier

4

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Stéphanie Tardif

5

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Amélie Tourette

6

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Marie-Christine Ailhaud

7

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Didier Cussac

8

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

publication date

6 August 2008

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Naunyn-Schmiedeberg's Archives of Pharmacology

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

379

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

1

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

87-99

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

Differential profile of antipsychotics at serotonin 5-HT1A and dopamine D2S receptors coupled to extracellular signal-regulated kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Dopamine D(4) and D(2L) Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent on trans-Activation of the Platelet-Derived Growth Factor Receptor

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The classification of seven transmembrane receptors in recombinant expression systems

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Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5).

1 reference

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The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus

1 reference

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12 December 2020

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Stimulation by antipsychotic agents of mitogen-activated protein kinase (MAPK) coupled to cloned, human (h)serotonin (5-HT)(1A) receptors

1 reference

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Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently

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Ligand-directed signaling at the beta3-adrenoceptor produced by 3-(2-Ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S-2-propanol oxalate (SR59230A) relative to receptor agonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Kinetic analysis of the interactions of agonists and antagonists with beta adrenergic receptors

1 reference

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12 December 2020

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Coupling efficacy and selectivity of the human mu-opioid receptor expressed as receptor-Galpha fusion proteins in Escherichia coli.

1 reference

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12 December 2020

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Affinities and intrinsic activities of dopamine receptor agonists for the hD21 and hD4.4 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Polymorphisms of the dopamine D4 receptor and response to antipsychotic drugs.

1 reference

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12 December 2020

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Dopamine D4 receptors: beyond schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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SH3 binding domains in the dopamine D4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Dopamine D4 receptor signaling in the rat paraventricular hypothalamic nucleus: Evidence of natural coupling involving immediate early gene induction and mitogen activated protein kinase phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

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F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. III. Activity in models of cognition and negative symptoms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Agonist and inverse agonist actions of beta-blockers at the human beta 2-adrenoceptor provide evidence for agonist-directed signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy

1 reference

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12 December 2020

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Cloning, expression, functional coupling and pharmacological characterization of the rat dopamine D 4 receptor

1 reference

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12 December 2020

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Agonist-directed trafficking of response by endocannabinoids acting at CB2 receptors

1 reference

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12 December 2020

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MAPK signal specificity: the right place at the right time

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Dopamine receptor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

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Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

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G protein-coupled receptor-mediated ERK1/2 phosphorylation: towards a generic sensor of GPCR activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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The dopamine D4 receptors and mechanisms of antipsychotic atypicality.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human beta-3 adrenergic receptor: new pharmacological profile and mechanism of activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Functional selectivity of D2 receptor ligands in a Chinese hamster ovary hD2L cell line: evidence for induction of ligand-specific receptor states

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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5-HT1A receptors mediate (+)8-OH-DPAT-stimulation of extracellular signal-regulated kinase (MAP kinase) in vivo in rat hypothalamus: time dependence and regional differences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

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The dopamine D(4) receptor: one decade of research

1 reference

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12 December 2020

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Characterization of dopaminergic compounds at hD2short, hD4.2 and hD4.7 receptors in agonist-stimulated [35S]GTPgammaS binding assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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G-protein-coupled receptor heterodimers: pharmacology, function and relevance to drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WAY-100635 has high selectivity for serotonin 5-HT(1A) versus dopamine D(4) receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

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Functional selectivity through protean and biased agonism: who steers the ship?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Functional activation by central monoamines of human dopamine D(4) receptor polymorphic variants coupled to GIRK channels in Xenopus oocytes

1 reference

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12 December 2020

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L-745,870 suppresses the nighttime serotonin N-acetyltransferase activity in chick retina: in vivo evidence for agonist activity at D4-dopamine receptors

1 reference

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12 December 2020

based on heuristic

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Action of novel antipsychotics at human dopamine D3 receptors coupled to G protein and ERK1/2 activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

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D(4) dopamine receptor differentially regulates Akt/nuclear factor-kappa b and extracellular signal-regulated kinase pathways in D(4)MN9D cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

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Agonist and antagonist properties of antipsychotics at human dopamine D4.4 receptors: G-protein activation and K+ channel modulation in transfected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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[35S]Guanosine-5'-O-(3-thio)triphosphate binding as a measure of efficacy at human recombinant dopamine D4.4 receptors: actions of antiparkinsonian and antipsychotic agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

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Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682919

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-008-0333-4

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18682919

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