(Q40724494)

23 September 2017

title

Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently (English)

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23 September 2017

Dominique Massotte

1

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author name string

Karl Brillet

series ordinal

2

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23 September 2017

Brigitte Kieffer

series ordinal

3

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23 September 2017

Graeme Milligan

series ordinal

4

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23 September 2017

language of work or name

English

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publication date

1 June 2002

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Journal of Neurochemistry

23 September 2017

number of pages

11

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based on heuristic

inferred from page(s)

published in

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23 September 2017

volume

81

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23 September 2017

issue

6

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23 September 2017

page(s)

1372-1382

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Hydrophobicity of residue351 of the G protein Gi1 alpha determines the extent of activation by the alpha 2A-adrenoceptor.

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling

21 January 2018

1 reference

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Agonist occupation of an alpha2A-adrenoreceptor-Gi1alpha fusion protein results in activation of both receptor-linked and endogenous Gi proteins. Comparisons of their contributions to GTPase activity and signal transduction and analysis of receptor-

21 January 2018

1 reference

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Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain

21 January 2018

1 reference

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Immunoprecipitation of high-affinity, guanine nucleotide-sensitive, solubilized mu-opioid receptors from rat brain: coimmunoprecipitation of the G proteins G(alpha o), G(alpha i1), and G(alpha i3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Activation of Type II Adenylyl Cyclase by the Cloned μ‐Opioid Receptor: Coupling to Multiple G Proteins

21 January 2018

1 reference

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Activation of mitogen-activated protein kinase by membrane-targeted Raf chimeras is independent of raft localization

21 January 2018

1 reference

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Opioid receptor signalling mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Antagonists of excitatory opioid receptor functions enhance morphine's analgesic potency and attenuate opioid tolerance/dependence liability

21 January 2018

1 reference

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Immunoprecipitation of opioid receptor-Go-protein complexes using specific GTP-binding-protein antisera

21 January 2018

1 reference

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Distinct roles for Galpha(i)2 and Gbetagamma in signaling to DNA synthesis and Galpha(i)3 in cellular transformation by dopamine D2S receptor activation in BALB/c 3T3 cells

21 January 2018

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Reporter-gene systems for the study of G-protein-coupled receptors.

21 January 2018

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Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis.

21 January 2018

1 reference

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Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras

21 January 2018

1 reference

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G(i1) and G(oA) differentially determine kinetic efficacies of agonists for kappa-opioid receptor

21 January 2018

1 reference

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mu and delta opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells

21 January 2018

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The role of members of the pertussis toxin-sensitive family of G proteins in coupling receptors to the activation of the G protein-gated inwardly rectifying potassium channel

21 January 2018

1 reference

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Delta-opioid-receptor-mediated inhibition of adenylate cyclase is transduced specifically by the guanine-nucleotide-binding protein Gi2

21 January 2018

1 reference

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Insights into ligand pharmacology using receptor-G-protein fusion proteins

21 January 2018

1 reference

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The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

A mitogen-activated protein kinase pathway is required for mu-opioid receptor desensitization

21 January 2018

1 reference

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Properties of a kappa-opioid receptor expressed in CHO cells: interaction with multiple G-proteins is not specific for any individual G alpha subunit and is similar to that of other opioid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Agonists determine the pattern of G-protein activation in mu-opioid receptor-mediated supraspinal analgesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Examining the efficiency of receptor/G-protein coupling with a cleavable beta2-adrenoceptor-gsalpha fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Fusion of beta 2-adrenergic receptor to G alpha s in mammalian cells: identification of a specific signal transduction species not characteristic of constitutive activation or precoupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Coupling efficacy and selectivity of the human mu-opioid receptor expressed as receptor-Galpha fusion proteins in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Coordinated agonist regulation of receptor and G protein palmitoylation and functional rescue of palmitoylation-deficient mutants of the G protein G11alpha following fusion to the alpha1b-adrenoreceptor: palmitoylation of G11alpha is not required fo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Opioid receptor endocytosis and activation of MAP kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Coupling of the muscarinic m2 receptor to G protein-activated K(+) channels via Galpha(z) and a receptor-Galpha(z) fusion protein. Fusion between the receptor and Galpha(z) eliminates catalytic (collision) coupling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Quantitative analysis of formyl peptide receptor coupling to g(i)alpha(1), g(i)alpha(2), and g(i)alpha(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Rescue of functional interactions between the alpha2A-adrenoreceptor and acylation-resistant forms of Gi1alpha by expressing the proteins from chimeric open reading frames.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

Interactions of the alpha2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

The rat D4 dopamine receptor couples to cone transducin (Galphat2) to inhibit forskolin-stimulated cAMP accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2002.00946.X

10.1046/J.1471-4159.2002.00946.X

21 January 2018

Identifiers

DOI

1 reference

23 September 2017

1 reference