(Q46445872)

22 December 2017

title

Tau Oligomers as Pathogenic Seeds: Preparation and Propagation In Vitro and In Vivo (English)

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22 December 2017

author name string

Julia E Gerson

series ordinal

1

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22 December 2017

Urmi Sengupta

series ordinal

2

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22 December 2017

Rakez Kayed

series ordinal

3

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22 December 2017

language of work or name

English

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publication date

1 January 2017

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22 December 2017

Methods in Molecular Biology

published in

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22 December 2017

volume

1523

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22 December 2017

page(s)

141-157

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22 December 2017

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice.

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Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

21 January 2018

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What is the pathological significance of tau oligomers?

21 January 2018

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Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain

21 January 2018

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Granular tau oligomers as intermediates of tau filaments

21 January 2018

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Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro

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Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.

21 January 2018

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Differential assembly of human tau isoforms in the presence of arachidonic acid

21 January 2018

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Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation

21 January 2018

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Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

21 January 2018

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Preparation and Characterization of Neurotoxic Tau Oligomers

21 January 2018

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Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

21 January 2018

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Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds

21 January 2018

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The role of tau in the pathological process and clinical expression of Huntington's disease

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Accelerated neurodegeneration through chaperone-mediated oligomerization of tau.

21 January 2018

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Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model.

21 January 2018

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Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles.

21 January 2018

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Characterization of tau oligomeric seeds in progressive supranuclear palsy

21 January 2018

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Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

21 January 2018

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Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies

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Template-assisted filament growth by parallel stacking of tau.

21 January 2018

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Side chain-dependent stacking modulates tau filament structure

21 January 2018

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

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Poloxamer 188 copolymer membrane sealant rescues toxicity of amyloid oligomers in vitro

21 January 2018

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Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

21 January 2018

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10.1007/978-1-4939-6598-4_9

21 January 2018

Identifiers

DOI

1 reference

22 December 2017

1 reference

22 December 2017